Inactivation of Aconitase by Fluoroacetate. Introduction: The 2R, 3R-fluorocitrate inactivates the aconitase. In the citrate synthase reaction, fluoroacetate results in the formation of fluorocitrate. The stoichiometric release of fluoride ion accompanied the inactivation by the fluorocitrate.

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Chapter 19, Problem 19P

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Inactivation of Aconitase by Fluoroacetate.

Introduction:

The 2R, 3R-fluorocitrate inactivates the aconitase. In the citrate synthase reaction, fluoroacetate results in the formation of fluorocitrate. The stoichiometric release of fluoride ion accompanied the inactivation by the fluorocitrate.

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