Human Anatomy & Physiology
1st Edition
ISBN: 9780805382952
Author: Erin C. Amerman
Publisher: PEARSON
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Chapter 19, Problem 2CYU
Summary Introduction
To review:
The effect of abnormal hemoglobin protein (carrying only two iron ions instead of four) on homeostasis.
Introduction:
Erythrocytes contain about one billion molecules of oxygen binding protein hemoglobin (Hb). The hemoglobin consists of four polypeptide subunits: two alpha
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Chapter 19 Solutions
Human Anatomy & Physiology
Ch. 19.1 - Prob. 1QCCh. 19.1 - Prob. 2QCCh. 19.1 - 3. How does blood regulate temperature and...Ch. 19.1 - 4. What are the four main categories of plasma...Ch. 19.1 - Prob. 5QCCh. 19.2 - Describe the structure of a typical erythrocyte.Ch. 19.2 - Prob. 2QCCh. 19.2 - 3. Walk through the basic steps of...Ch. 19.2 - 4. What is the lifespan of an erythrocyte?
Ch. 19.2 - Prob. 5QC
Ch. 19.2 - Prob. 6QCCh. 19.2 - Prob. 7QCCh. 19.3 - How do granulocytes and agranulocytes differ?Ch. 19.3 - Prob. 2QCCh. 19.3 - Compare the two types of agranulocytes.Ch. 19.3 - 4. How do B and T lymphocytes differ?
Ch. 19.3 - 5. What does a monocyte become in the tissues?...Ch. 19.3 - Prob. 6QCCh. 19.3 - 7. How do the lymphoid and myeloid cell lines...Ch. 19.3 - 8. Where do T and B lymphocytes mature?
Ch. 19.4 - Prob. 1QCCh. 19.4 - Prob. 2QCCh. 19.5 - Prob. 1QCCh. 19.5 - Prob. 2QCCh. 19.5 - 3. How are platelets triggered to aggregate?
Ch. 19.5 - Prob. 4QCCh. 19.5 - How do the intrinsic/contact activation and...Ch. 19.5 - Prob. 6QCCh. 19.5 - Prob. 7QCCh. 19.5 - What is thrombolysis?Ch. 19.5 - Prob. 9QCCh. 19.5 - Prob. 10QCCh. 19.5 - Prob. 11QCCh. 19.5 - Prob. 12QCCh. 19.5 - Prob. 13QCCh. 19.5 - Prob. 14QCCh. 19.6 - Prob. 1QCCh. 19.6 - Prob. 2QCCh. 19.6 - Prob. 3QCCh. 19.6 - Prob. 4QCCh. 19.6 - Prob. 5QCCh. 19 - Prob. 1CYRCh. 19 - Prob. 2CYRCh. 19 - List the seven major functions of blood.Ch. 19 - Prob. 4CYRCh. 19 - Prob. 5CYRCh. 19 - Prob. 6CYRCh. 19 - Prob. 7CYRCh. 19 - Leukocytes are: a. nucleated cells that function...Ch. 19 - Prob. 9CYRCh. 19 - Fill in the blanks: Lymphocytes are derived from...Ch. 19 - Prob. 11CYRCh. 19 - Number the steps of hemostasis in order, putting 1...Ch. 19 - Prob. 13CYRCh. 19 - Prob. 14CYRCh. 19 - Prob. 15CYRCh. 19 - Prob. 16CYRCh. 19 - Prob. 17CYRCh. 19 - 18. Which antigens does a person with blood type...Ch. 19 - Prob. 19CYRCh. 19 - Prob. 20CYRCh. 19 - 1. Explain how blood, being a liquid, enables all...Ch. 19 - Prob. 2CYUCh. 19 - 3. The anticoagulant drug warfarin primarily...Ch. 19 - 4. Cirrhosis of the liver often reduces production...Ch. 19 - 1. A blood sample from your patient shows that she...Ch. 19 - Prob. 2AYKACh. 19 - Prob. 3AYKACh. 19 - Prob. 4AYKB
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- Sickle cells are named because of their characteristic shape. What problems can this shape cause? Explain how the absence of a nucleus affects a red blood cell’s life span.arrow_forwarda) Hemoglobin accounts for 95% of the protein in red blood cells. If you Google the number of hemoglobin molecules in a RBC, most sources state 250-270 million hemoglobin molecules. If hemoglobin has a molecular weight of 67,000 Da, what is the concentration of hemoglobin in RBCs? Show your work and show your units. Use dimensional analysis to have your final answer in moles per liter. B) The hemoglobin molecule is nearly spherical with a diameter of 55 Angstroms. You can look at the 3D structure of human hemoglobin on the RCSB PDB website. Calculate the volume of a hemoglobin molecule, and can the number of hemoglobin molecules quoted in Question a actually fit into one red blood cell?arrow_forwardHemoglobin can exist in one of two forms. What are they?arrow_forward
- Hemoglobin will bind oxygen and release CO2 in places where there is a higher concentration of O2, lower concentration of CO2, lower temperature and lower acidity (as it is in lungs) and will do the reverse – release oxygen and bind CO2 - in places where there is a lower concentration of O2, higher concentration of CO2, higher temperature and higher acidity (as it is in working muscles). True False While white blood cells never leave the circulation, red blood cells regularly leave it and travel by lymphatic system or find home in other tissues, e.g., lymph nodes, spleen, etc. True False Blood clotting (coagulation) is a complex process involving many factors and it exhibits positive feedback loops: many of the factors also stimulate production of their own precursors. B lymphocytes mature in the thymus while T lymphocytes mature in the bone marrow True False Antibodies are molecules on the surfaces of foreign…arrow_forwardList two structural adaptions of red blood cell to explain how these structural adaptions make them specialized for transporting oxygen?arrow_forwardMatch the following with its function: plasma protein that creates osmotic pressure that prevents fluids from leaking out of blood vessels (prevents edema) A. albumin B. fibrinogen plasma protein that helps cause blood clotting C. platelets v Formed element that causes blood clotting. D. white blood cells Formed element important in the immune E. red blood cells system. F. hemoglobin v formed element that carries oxygen v protein that binds to oxygenarrow_forward
- in thalassemia, a type of anemia, the hemoglobin molecule is malformed. The malformation prevents hemoglobin from carrying and delivering the correct amount of oxygen to the cells. Which important physiological concept does this example illustrate?arrow_forwardWhich five statements about hemoglobin and myoglobin structure are true? Each iron atom can form six coordination bonds. Two of these bonds are formed between iron and oxygen. Molecular oxygen binds reversibly to Fe²+ in heme. Heme is composed of an organic protoporphyrin component and a metal atom. By itself, heme is not a good oxygen carrier. It must be part of a larger protein to prevent oxidation of the iron atom. Each hemoglobin or myoglobin molecule can bind four oxygen molecules. Hemoglobin is a heterotetramer, whereas myoglobin is a monomer. Both hemoglobin and myoglobin contain a prosthetic group called heme, which contains a central iron atom.arrow_forwardWhat are the conditions under which hemoglobin precipitates out of solution, and how are normal and sickle-cell hemoglobin different in that regard? What do you predict will happen to red blood cells if hemoglobin precipitates out of solution and crystallizes?arrow_forward
- In which of the following disorders, blood has a defective hemoglobin? A Hematoma B Hematuria C Hemophilia D Sickle cell anemiaarrow_forwardCan all abnormal hemoglobin be diagnosed by electrophoresis ?Explain why or why not .arrow_forwardThe hemoglobin of a human fetus differs from adult hemoglobin. Compare the dissociation curves of the two hemoglobins in the graph at right. Describe how they differ, and propose a hypothesis to explain the benefit of this difference.arrow_forward
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