Essential Organic Chemistry, Global Edition
Essential Organic Chemistry, Global Edition
3rd Edition
ISBN: 9781292089034
Author: Paula Yurkanis Bruice
Publisher: PEARSON
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Chapter 19, Problem 24P
Interpretation Introduction

Interpretation:

The mechanism for the synthesis of fatty acyl-CoA with the help of the enzyme Acyl-CoAsynthase has to be proposed.

Concept Introduction:

  Glycolysis: It is pathway which describes conversion of one molecule of glucose into two molecules of pyruvate. The series involves 10 reactions.

NAD+Molecule: It is the oxidized form of Nicotinamide adenine dinucleotide (NAD) which exists in all cells and needed for activation of enzymes.

NADHmolecule: It is coenzyme which gets oxidized on reducing another compound. The oxidized form of NADHisNAD+.

Fatty acid conversion to fatty acyl-CoA: Many steps are involved in the catabolism of fats in our body.  A fatty acid formed can be converted into fatty acyl-CoA in the presence of an enzyme called Acyl-CoAsynthase.  The fatty acid should be activated before it can be metabolized.

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The rate-limiting step is a metabolic pathway is the slowest step which determines the overall rate of the other reactions in the pathway. In glycolysis, the rate limiting step is a phosphorylation reaction where phosphofructokinase (PFK-1) catalyzes the reaction fructose-6-bisphosphate -> fructose-1,6-bisphosphate, the same step in gluconeogenesis. Select one: The statement is FALSE. The statement is TRUE.
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