Genetic Analysis: An Integrated Approach (2nd Edition)
2nd Edition
ISBN: 9780321948908
Author: Mark F. Sanders, John L. Bowman
Publisher: PEARSON
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Chapter 19, Problem 18P
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A woman knows that her mother is a carrier of Kartagener’s syndrome (an autosomal recessive disorder). The woman does not know if either she or her husband are carriers. The couple wants to have a child, but is worried about whether or not they could have a child with Kartagener’s syndrome. Should the couple seek the advice of a genetic counselor? In other words, is there a chance they could have an affected child? If there is a chance, please make sure your answer includes the specific parental genotypes necessary to make this possible.
A genetic counsellor is working with a couple who have just had a child who has a debilitating autosomal recessive form of a disease
termed epidemolysis bullosa (which causes severe external and internal skin fragility resulting in blistering etc). Neither parent has
epidemolysis bullosa, nor does anyone in their families. What should the counsellor say to this couple?
OA. "Because no one in either of your families has epidemolysis bullosa, you are not likely to have another baby with epidemolysis
bullosa. You can safely have another child."
OB. "Because you have had one child with epidemolysis bullosa, you must each carry the allele. Any child you have has a 50%
chance of having the disease."
OC. "Because you have had one child with epidemolysis bullosa, you must
each carry the allele. Any child you have has a 25% chance of having the disease."
OD. "Because you have had one child with epidemolysis bullosa, you must both carry the allele. However, since the chance of having
an affected…
A 20-year-old woman comes to your genetic counselling center because she knows that Huntington disease occurs in members of her family. Huntington is an autosomal dominant disease that often becomes apparent around 35–40 years of age. Her paternal grandfather was afflicted, but so far her 41 year old father shows no symptoms. Her two great-great grandmothers on her father's side were healthy well into their 90s, and one of her great-great grandfathers died of unknown causes at 45. Testing for Huntington disease is extremely expensive, but she is concerned that she may fall victim to this disease and wants to plan her life accordingly. After examining her pedigree you advise her to:
not get tested because her father is only a carrier and it is very unlikely her mother is a carrier.
not get tested because there is no possibility that she is homozygous.
get tested because her father could be a carrier.
not get tested because only males in her family get the disease.
not get tested…
Chapter 19 Solutions
Genetic Analysis: An Integrated Approach (2nd Edition)
Ch. 19 - 17.1 Reciprocal crosses of experimental animals or...Ch. 19 - 17.2 How are some of the characteristics of the...Ch. 19 - 17.3 The human mitochondrial genome encodes...Ch. 19 - What is the evidence that transfer of DNA from the...Ch. 19 - Draw a graph depicting the relative amounts of...Ch. 19 - Prob. 6PCh. 19 - 17.7 What is the evidence that the ancient...Ch. 19 - 17.8 Outline the steps required for a gene...Ch. 19 - 17.9 Consider the phylogenetic tree presented in...Ch. 19 - Most large protein complexes in mitochondria and...
Ch. 19 - What insights have analyses of human mitochondrial...Ch. 19 - You are a genetic counselor, and several members...Ch. 19 - A mutation in Arabidopsis immutans results in the...Ch. 19 - What type or types of inheritance are consistent...Ch. 19 - You have isolated (1) a streptomycin-resistant...Ch. 19 - You have isolated two petite mutants, pet1 and...Ch. 19 - 17.15 Consider this human pedigree for a vision...Ch. 19 - A 50- year - old man has been diagnosed with MELAS...Ch. 19 - 17.17 The first person in a family to exhibit...Ch. 19 - Prob. 20PCh. 19 - Prob. 21PCh. 19 - 17.19 What is the most likely mode of inheritance...Ch. 19 - 17.20 In , the Russian Tsar Nicholaswas deposed,...Ch. 19 - 17.21 The dodo bird (Raphus cucullatus) lived on...Ch. 19 - Cytoplasmic male sterility (CMS) in plants has...Ch. 19 - 17.23 Wolves and coyotes can interbreed in...Ch. 19 - Prob. 27PCh. 19 - Prob. 28P
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