Concept explainers
(1)
To determine:
The reasons that government can cite for maintaining smallpox viruses.
Concept introduction:
The United States and Russia have repeatedly agreed to destroy their stocks of the smallpox virus, but the deadline has been put off many times. In the meantime, the entire genome of variola virus has been sequenced. Smallpox is an infectious disease of the past that was eliminated worldwide by vaccination. Affected people become ill with high fever and rashes.
(2)
To determine:
Whether laboratory stores of smallpox viruses should be destroyed.
Concept introduction:
The United States and Russia have repeatedly agreed to destroy their stocks of the smallpox virus, but the deadline has been put off many times. In the meantime, the entire genome of variola virus has been sequenced. Smallpox is an infectious disease of the past that was eliminated worldwide by vaccination. Affected people become ill with high fever and rashes.
(3)
To determine:
Weather elimination of all laboratories stock really be the extinction of smallpox virus.
Concept introduction:
The United States and Russia have repeatedly agreed to destroy their stocks of the smallpox virus, but the deadline has been put off many times. In the meantime, the entire genome of variola virus has been sequenced. Smallpox is an infectious disease of the past that was eliminated worldwide by vaccination. Affected people become ill with high fever and rashes.
Want to see the full answer?
Check out a sample textbook solutionChapter 19 Solutions
Microbiology with Diseases by Body System (5th Edition)
- 7) List 5 ways that the current novel coronavirus and the disease it causes is similar to the influenza virus: A) B) C) D) E) 8) List 5 ways that the current novel coronavirus and the disease it causes differs from the influenza virus: A) B) C) D) E) Questions related to mRNA vaccines 1) What macromolecule is usually used as part of a vaccine? 2) What are advantages of using mRNA vaccines?arrow_forwardWhat would happen to a virus that found its way to an environment filled only with cells that were outside of its host range? a) This virus would evolve until it was able to use the surrounding cells as hosts b) This virus would actively transport itself to another area in search of host cells C) This virus would replicate until it found cells that were within its host range d) Nothing; this virus would not be replicatedarrow_forwardCoronaviruses have a positive-sense single stranded RNA genome. a.) What is the genome replication strategy of this category of viruses? b.) How do you think this feature affects the stability of the viral genome? (hint use figure below) Mutation rates in different types of viruses. Estimates obtained for viruses belonging to the major indicated groups are shown as a function of genome size. This reveals an effect of genetic material (RNA/DNA) and genome size on viral mutation rates.arrow_forward
- Which of the following is NOT a feature of genetic reassortment? A) a host cell is coinfected with two different viruses B) different segments of multipartite genomes are mixed C) host range is permanently altered D) two different viruses have nonidentical but overlapping host ranges E) viruses released possess genetic material from two “parent” viruses F) ALL of these are features of genetic reassortmentarrow_forwardSome retroviruses that have a wide host range have been developed for use in treatment of diseases or syndromes. These viruses do not result in a productive infection because they lack critical genes for viral replication, but they do carry DNA sequences that allow them to be packaged into infectious particles. Once in the host cell the viral DNA is released and integrates into the cell's genome. The advantage to this strategy is that the delivery of the DNA is very efficient. What is one possible problem of using a virus that can integrate into the human nuclear genome? Multiple Choice The virus carries genes that will interfere with host cell activities. The viral DNA sequences could still cause a disease. Since the viral DNA sequences no longer contain essential genes for viral replication the host cell may not be able to replicate either. The integration could disrupt an essential gene or genes.arrow_forwardModerna and Pfizer vaccines for COVID-19 use mRNA to the Spike protein combined with lipids. Which of the following is/are advantages of this type of vaccine compared to an inactivated virus vaccine? Select ALL correct answers. a) The vaccine is more stable for transport. b) The vaccine does not contain the virus so it cannot give you COVID-19. c) The vaccine can be rapidly produced in a slightly different form to protect from variants of SARS-CoV-2. d) The vaccine does not need a booster.arrow_forward
- Influenza vaccines must be changed yearly because the amino acid sequence of the viral proteins change gradually over time. Based on this information, which is the most logical conclusion? The influenza virusa) is enveloped. b) is non-enveloped.c) has a DNA genome. d) has an RNA genome.e) causes a persistent infection.arrow_forwardThe complete coronavirus genome sequence from the first known patient infected with SARS-CoV-2 was published on January 10th 2020, just a short time after the patient had been hospitalized in China with respiratory symptoms. They did this so quickly using nanopore sequencing. Scientists compared the genome sequence from the new coronavirus (SARS-CoV-2) with the genome sequences from several other coronaviruses and they did identify a sequence unique to the SARS-CoV-2 strain. This unique sequence was in the N gene of the viral genome. What protein is made from the N gene of the virus?arrow_forwardThis figure shows the frequency of the different variants of the novel coronavirus over time colored as each variant. I need help understanding what the figure tells me about the relative fitnesses of the delta variant compared to the alpha variant?arrow_forward
- Match each of the following replication classes of viruses with the one description that best describes it. This virus class is composed of segmented and non-segmented helical viruses that carry an RdRp within the virion into the cell. Example: Rabies virus These viruses are non- enveloped, icosahedral, have segmented genomes, and carry their own RNA-dependent RNA polymerase. The viral genome is copied following assembly. Example: Reovirus This is the only class of RNA viruses whose genome is replicated by cellular enzymes and not an RNA-dependent RNA polymerase. Cellular DNA polymerases replicate this virus's non- integrated genome, although transcription is not the initial event that takes place in the process. Example: Parvoviruses In this class of viruses, transcription occurs before genome replication because viral proteins are involved in replicating the genome. Example: Adenovirus This class of viruses forms circular DNA and creates pre- genomic RNA using host RNA polymerases.…arrow_forwardWhen Wimmer and coworkers announced that they had synthesized the poliovirus, they created considerable controversy. Some people feared that deadly and highly contagious viruses might be synthesized by bioterrorists. The researchers responded that they were merely applying current knowledge and techniques to demonstrate the principle that viruses are basically chemical entities that can be synthesized in the laboratory. Do you think scientists should synthesize viruses or other agents that can cause infectious disease? What are the implications of forbidding such research?arrow_forwardWhich of the following statements regarding retroviruses is FALSE? A) a cellular enzyme converts the RNA genome into DNA B) double-stranded DNA is transcribed into mRNA by cellular enzymes C) retroviral genomes consist of positive-sense RNA D) the virus commonly integrates into the host chromosome as a provirus E) viral RNA enters the nucleus F) ALL of these statements are TRUEarrow_forward
- Human Anatomy & Physiology (11th Edition)BiologyISBN:9780134580999Author:Elaine N. Marieb, Katja N. HoehnPublisher:PEARSONBiology 2eBiologyISBN:9781947172517Author:Matthew Douglas, Jung Choi, Mary Ann ClarkPublisher:OpenStaxAnatomy & PhysiologyBiologyISBN:9781259398629Author:McKinley, Michael P., O'loughlin, Valerie Dean, Bidle, Theresa StouterPublisher:Mcgraw Hill Education,
- Molecular Biology of the Cell (Sixth Edition)BiologyISBN:9780815344322Author:Bruce Alberts, Alexander D. Johnson, Julian Lewis, David Morgan, Martin Raff, Keith Roberts, Peter WalterPublisher:W. W. Norton & CompanyLaboratory Manual For Human Anatomy & PhysiologyBiologyISBN:9781260159363Author:Martin, Terry R., Prentice-craver, CynthiaPublisher:McGraw-Hill Publishing Co.Inquiry Into Life (16th Edition)BiologyISBN:9781260231700Author:Sylvia S. Mader, Michael WindelspechtPublisher:McGraw Hill Education