Biochemistry, The Molecular Basis of Life, 6th Edition
6th Edition
ISBN: 9780190259204
Author: Trudy McKee, James R. McKee
Publisher: Oxford University Press
expand_more
expand_more
format_list_bulleted
Concept explainers
Videos
Question
Chapter 18, Problem 57SA
Summary Introduction
To explain:
The telomerase activity is higher in cancer cell than in normal somatic cells.
Introduction:
Telomerase is an enzyme, also referredas terminal transferase. It is ribonucleoprotein found in adult germ cells, somatic cells, fetal tissue, snd tumor cells. It is active in most cancer cells and less active in somatic cells. Its main function is to restore the telomeres (short stretches of DNA) that become shorter when a cell divides.
Expert Solution & Answer
Want to see the full answer?
Check out a sample textbook solution
Students have asked these similar questions
7. a. Complete the following redox reaction with the missing products
NADH H
b. Provide an arrow-pushing mechanism for the oxidation reaction. Use the explicit structure of
NADH or NAD' as needed. For simplicity, use only the nicotinamide portion of the molecule
Discuss the differences between eukaryotic and prokaryotic cells with regards to their genetic materials. Including in your discussion the structure and organisation of genetic material, as well as any implications these differences may have on cellular functions and evolution.
Rubric
Understanding of genetic material differences (provides a comprehensive and accurate explanation of the differences between eukaryotic and prokaryotic cells in terms of their genetic material, including the structure, organisation and function of genetic material in each cell type. Demonstrates a thorough understanding of the topic)
Analysis of implications (analyze the differences between eukaryotic and prokaryotic cells in terms of their genetic material with depth and insight, discussing the implications of these differences on cellular functions and evolution. Provides specific examples and explanations.)
When was the dihydropyridine calcium channel blocker isradipine first patented and by whom? Please provide information on the origin and history of isradipine and who owns it/manufactures it.
Chapter 18 Solutions
Biochemistry, The Molecular Basis of Life, 6th Edition
Ch. 18 - Prob. 1QCh. 18 - Prob. 2QCh. 18 - Prob. 3QCh. 18 - Prob. 4QCh. 18 - Prob. 5QCh. 18 - Prob. 1RQCh. 18 - Prob. 2RQCh. 18 - Prob. 3RQCh. 18 - Prob. 4RQCh. 18 - Prob. 5RQ
Ch. 18 - Prob. 6RQCh. 18 - Prob. 7RQCh. 18 - Prob. 8RQCh. 18 - Prob. 9RQCh. 18 - Prob. 10RQCh. 18 - Prob. 11RQCh. 18 - Prob. 12RQCh. 18 - Prob. 13RQCh. 18 - Prob. 14RQCh. 18 - Prob. 15RQCh. 18 - Prob. 16RQCh. 18 - Prob. 17RQCh. 18 - Prob. 18RQCh. 18 - Prob. 19RQCh. 18 - Prob. 20RQCh. 18 - Prob. 21RQCh. 18 - Prob. 22RQCh. 18 - Prob. 23RQCh. 18 - Prob. 24RQCh. 18 - Prob. 25RQCh. 18 - Prob. 26RQCh. 18 - Prob. 27RQCh. 18 - Prob. 28RQCh. 18 - Prob. 29RQCh. 18 - Prob. 30RQCh. 18 - Prob. 31RQCh. 18 - Prob. 32RQCh. 18 - Prob. 33RQCh. 18 - Prob. 34RQCh. 18 - Prob. 35RQCh. 18 - Prob. 36RQCh. 18 - Prob. 37RQCh. 18 - Prob. 38RQCh. 18 - Prob. 39RQCh. 18 - Prob. 40RQCh. 18 - Prob. 41RQCh. 18 - Prob. 42RQCh. 18 - Prob. 43RQCh. 18 - Prob. 44RQCh. 18 - Prob. 45RQCh. 18 - Prob. 46RQCh. 18 - Prob. 47FBCh. 18 - Prob. 48FBCh. 18 - Prob. 49FBCh. 18 - Prob. 50FBCh. 18 - Prob. 51FBCh. 18 - Prob. 52FBCh. 18 - Prob. 53FBCh. 18 - Prob. 54FBCh. 18 - Prob. 55FBCh. 18 - Prob. 56FBCh. 18 - Prob. 57SACh. 18 - Prob. 58SACh. 18 - Prob. 59SACh. 18 - Prob. 60SACh. 18 - Prob. 61SACh. 18 - Prob. 62TQCh. 18 - Prob. 63TQCh. 18 - Prob. 64TQCh. 18 - Prob. 65TQCh. 18 - Prob. 66TQCh. 18 - Prob. 67TQCh. 18 - Prob. 68TQCh. 18 - Prob. 69TQCh. 18 - Prob. 70TQCh. 18 - Prob. 71TQCh. 18 - Prob. 72TQCh. 18 - Prob. 73TQCh. 18 - Prob. 74TQCh. 18 - Prob. 75TQ
Knowledge Booster
Learn more about
Need a deep-dive on the concept behind this application? Look no further. Learn more about this topic, biochemistry and related others by exploring similar questions and additional content below.Similar questions
- 9) Below, there is a representation of an SDS-PAGE gel. Assuming the samples in the MW standard have masses of: 66 kDa, 45 kDa, 36 kDa, 29 kDa, 24 kDa, 20.1 kDa, and 14.2 kDa, a) Figure 4: indicate where each of the measurements were taken and label as in II.6. figure 2 above. b) As in II.7. Table 1 above create Table 2 using the data below. Determine the r.f. values for the MW standards, plot the relative mobility versus the log of the mass for the standards, and use the best fit straight line to determine the molecular weights of the proteins in the whey, peak 1, and peak 2 lanes. (5 pts—this will be scaled up appropriately if your gel did not develop properly) dye MW Whey Peak 1 Peak 2arrow_forwardwhat are the different classes and some examples of neuroprotectants that can be used to treat, prevent, or combat neurotoxicity/a neurotoxicant...for example, antioxidants, nutraceuticals, etc.,..?arrow_forwardImagine that aldolase can react with the seven carbon molecule Sedoheptulose-1,7-bisphosphate (below). Use the mechanism to predict the two products generated. Please draw out the stereochemistry in a fischer projection.arrow_forward
- Sodium borohydride (NaBH4) is a potent inhibitor of aldolase. It is known to ONLY inhibit theenzyme when it is complexed with substrate. Treatment of the enzyme alone has no effect.What is the mechanism for this inhibition? Please draw out the mechanism and show how it inhibits this.arrow_forwardShow the fate of the proton on the 4-Oxygen molecule of F-1,6-BP. Please include a drawing showing the electron flow that occurs.arrow_forward1. Which one is the major organic product obtained from the following aldol condensation? O NaOH, H₂O heat A B C D Earrow_forward
- An organic chemist ordered the wrong item. She wanted to obtain 1-hydroxy-2-butanone, butinstead ordered 2-hydroxybutyraldehyde. As a good biochemist, show how the organic chemistcould use biological catalysis to make her desired compound. Please show the mechanism by drawing.arrow_forwardShow the fate of the hydrogen on carbon-2 of glucose. Please draw out the structure using curve arrows to show electron flow.arrow_forward3. Which one of the compounds below is the major product formed by the reaction sequence shown here? CH3 + CH3NO2 NaOH H2, Ni ? nitromethane acetophenone OH OH HO HN- u x x x x Ph A HO -NH2 HO H Ph Ph Ph N- H B Ph NH2 D Earrow_forward
- 4. Only ONE of the five compounds below can be prepared by an aldol condensation in which a single carbonyl compound is treated with base. Which one is it? To solve this problem, reverse the aldol condensation that formed each of these molecules to find out what two molecules came together to make the products. The one in which the two molecules are identical is the answer. Ph Ph ཚིག གནས ག ནཱ ཀ ན ཀནཱ A Ph H B Ph Ph H D Ph. Ph Ph E Harrow_forward5. Which one is the major organic product obtained from the following reaction sequence? First, equimolar amounts of cyclopentanone and LDA are mixed at -78°C. Then propionaldehyde (propanal) is added. Addition of aqueous acid completes the process. LDA, -78°C. 1. 2. H₂O* H A B H 0 D H H Earrow_forward2. Which one is the major organic product obtained from the following reaction? NaOH, H₂O heat A B C D Earrow_forward
arrow_back_ios
SEE MORE QUESTIONS
arrow_forward_ios
Recommended textbooks for you
Biology 2eBiologyISBN:9781947172517Author:Matthew Douglas, Jung Choi, Mary Ann ClarkPublisher:OpenStax
BiochemistryBiochemistryISBN:9781305577206Author:Reginald H. Garrett, Charles M. GrishamPublisher:Cengage Learning
Human Heredity: Principles and Issues (MindTap Co...BiologyISBN:9781305251052Author:Michael CummingsPublisher:Cengage Learning
Biology Today and Tomorrow without Physiology (Mi...BiologyISBN:9781305117396Author:Cecie Starr, Christine Evers, Lisa StarrPublisher:Cengage Learning
Anatomy & PhysiologyBiologyISBN:9781938168130Author:Kelly A. Young, James A. Wise, Peter DeSaix, Dean H. Kruse, Brandon Poe, Eddie Johnson, Jody E. Johnson, Oksana Korol, J. Gordon Betts, Mark WomblePublisher:OpenStax College
Biology (MindTap Course List)BiologyISBN:9781337392938Author:Eldra Solomon, Charles Martin, Diana W. Martin, Linda R. BergPublisher:Cengage Learning
Biology 2e
Biology
ISBN:9781947172517
Author:Matthew Douglas, Jung Choi, Mary Ann Clark
Publisher:OpenStax
Biochemistry
Biochemistry
ISBN:9781305577206
Author:Reginald H. Garrett, Charles M. Grisham
Publisher:Cengage Learning
Human Heredity: Principles and Issues (MindTap Co...
Biology
ISBN:9781305251052
Author:Michael Cummings
Publisher:Cengage Learning
Biology Today and Tomorrow without Physiology (Mi...
Biology
ISBN:9781305117396
Author:Cecie Starr, Christine Evers, Lisa Starr
Publisher:Cengage Learning
Anatomy & Physiology
Biology
ISBN:9781938168130
Author:Kelly A. Young, James A. Wise, Peter DeSaix, Dean H. Kruse, Brandon Poe, Eddie Johnson, Jody E. Johnson, Oksana Korol, J. Gordon Betts, Mark Womble
Publisher:OpenStax College
Biology (MindTap Course List)
Biology
ISBN:9781337392938
Author:Eldra Solomon, Charles Martin, Diana W. Martin, Linda R. Berg
Publisher:Cengage Learning
QCE Biology: Introduction to Gene Expression; Author: Atomi;https://www.youtube.com/watch?v=a7hydUtCIJk;License: Standard YouTube License, CC-BY