Concept explainers
Interpretation:
The products A, B, C, and D formed from the sequence of steps from the given starting material, are to be determined.
Concept Introduction:
▸ LDA is the lithium disopyramide. It is a strong base.
▸ In
▸ Alkylation of the ketone takes place with the help of lithium enolates.
▸ Sodium hydride is used to generate the enolate ions.
▸ In the diels-alder reaction, two sigma bonds are formed from an expansion of the pi bond of the diene and dienophile.
▸ Ketones react with secondary
Trending nowThis is a popular solution!
Chapter 18 Solutions
Organic Chemistry
- Predict the major product or the necessary reagent or reactant to complete each of the following reactions. In the box before each reaction, indicate the mechanism followed by the reaction. (Free radical (FR), SN2, SN1). (b) (a) Cl₂ CH₂CH₂OH (a) 1 hv 2 (b) H Br H₂O Na+ SCH3 (c) (d) CI "CH3arrow_forwardCan i get help with these problemsarrow_forwardWhich of the following is the major product of the reaction below? (1) LDA/ether (2) (3) ethanol, A (A) (B) (C) (D) OCompound A Compound D Compound B Compound Carrow_forward
- Identify the reagents you would use to achieve of the following transformation. Identify these reactions as SN1 or Sn2. (a) (b) (c) (d)arrow_forward11. Propose an efficient synthesis for each of the following transformations. تی ہیں۔ (a) (b) H Harrow_forwardPlease explain how you arrived at the answer, thank you!arrow_forward
- Using your reaction roadmap as a guide, show how to convert cyclohexanol into racemic trans-1,2-cyclohexanediol. (1) (2) (3) OH OH trans-1,2-cyclohexanediol (racemic) Submit Answer Suggest reagents and experimental conditions for each step in this synthesis. From the choices provided, suggest appropriate reagents for each step. More than one reagent may be necessary. Use the minimum number of steps possible. Enter your answer as a letter, or a series of letters, in the order necessary to bring about the steps shown. Reagents: (c) ethylene oxide OH "OH (a) CH3O Na+, CH, OH (d) H₂SO4, H₂O (b) OsO4, H₂O2 Retry Entire Group OH (e) m-chloroperoxybenzoic acid (mCPBA) (f) pyridinium chlorochromate (PCC) + 9 more group attempts remaining 2 (9) H₂SO4 (anhydrous) (j) Na, NH3 (1) (h) NaOH (k) NBS, heat (i) PBr3 (N-bromosuccinimide) Previous Nextarrow_forwardPropose a suitable synthesis to accomplish the following transformations. Please give the reagents and products for every step. Do not just list the reagentsarrow_forwardplease write out answers and explanations to make it easy to understandarrow_forward
- Show how the following transformations may be accomplished in good yield. You may use any additional reagents that are needed. (a) bromobenzene - propiophenone (b) CH3CH2CN - heptan-3-onearrow_forwardThe bicyclo [3.1.0] hexane ring system, highlighted in compound 3, is found in several natural products, including sabinene, a compound partially responsible for the flavor of ground black pepper. One method for preparing this ring system involves the conversion of compound 1 to compound 2, as shown below. Draw the structure of compound 2 and provide a reasonable mechanism for its formation. What are the most likely steps in the mechanism to form product 2? a. protonate, protonate, nucleophilic attack, nucleophilic attack b. Nucleophilic attack, protonate, protonate, nucleophilic attack c. Nucleophilic attack, protonate, nucleophilic attack, protonate d. Protonate, nucleophilic attack, protonate, nucleophilic attackarrow_forwardWhich of the following compounds will not be formed in the reaction below? H3PO4 (A) (B) (C) (D) Compound B Compound C Compound Darrow_forward
- Organic ChemistryChemistryISBN:9781305580350Author:William H. Brown, Brent L. Iverson, Eric Anslyn, Christopher S. FootePublisher:Cengage Learning