(a)
Interpretation:
The complete, detailed mechanism and the major organic product for the given reaction is to be drawn.
Concept introduction:
When
Answer to Problem 18.68P
The complete, detailed mechanism and the major organic product for the given reaction is as shown below:
Explanation of Solution
The given reaction is as shown below:
The given reaction is a crossed aldol condensation as the nucleophilic species is generated from a different ketone than the one that is attacked. Firstly, the given ketone is treated with LDA to produce
The complete, detailed mechanism and the major organic product for the given reaction is as shown below:
The complete, detailed mechanism and the major organic product for given reaction is drawn by crossed aldol reaction followed by dehydration of
(b)
Interpretation:
The complete, detailed mechanism and the major organic product for given reaction is to be drawn.
Concept introduction:
When ketone is treated with sodium hydroxide, the product
Answer to Problem 18.68P
The complete, detailed mechanism and the major organic product for given reaction is as shown below:
Explanation of Solution
The given reaction is as shown below:
The given reaction is a crossed aldol reaction. In Step 1,
The complete, detailed mechanism and the major organic product for given reaction is drawn on the basis of crossed aldol reaction mechanism.
(c)
Interpretation:
The complete, detailed mechanism and the major organic product for given reaction is to be drawn.
Concept introduction:
When aldehyde is treated with sodium hydroxide, the product
Answer to Problem 18.68P
The complete, detailed mechanism and the major organic product for given reaction is as shown below:
Explanation of Solution
The given reaction is
The given reaction is intramolecular aldol condensation reaction as the sodium hydroxide and heat is given. The given aldehyde is treated with sodium hydroxide, to produce
The complete, detailed mechanism and the major organic product for the given reaction is as shown below:
The complete, detailed mechanism and the major organic product for given reaction is drawn on the basis of intramolecular aldol condensation reaction.
(d)
Interpretation:
The complete, detailed mechanism and the major organic product for given reaction is to be drawn.
Concept introduction:
When ketone is treated with strong base like LDA, the product enolate anion is formed. In Step 1, LDA deprotonates the
Answer to Problem 18.68P
The complete, detailed mechanism and the major organic product for given reaction is as shown below,
Explanation of Solution
The given reaction is
Firstly, the given ketone is treated with LDA, to produce
The complete, detailed mechanism and the major organic product for given reaction is as shown below,
The complete, detailed mechanism and the major organic product for given reaction is drawn by aldol addition reaction followed by dehydration of
Want to see more full solutions like this?
Chapter 18 Solutions
Organic Chemistry: Principles and Mechanisms (Second Edition)
- Draw the complete, detailed mechanism for the reaction shown here and predict the major product. CH3ONA Explain. DMSOarrow_forwardDraw the complete, detailed mechanism for the following reaction.arrow_forwardDraw the complete, detailed mechanism for each of the following reactions ( (b) NaOH ? U NaOH ?arrow_forward
- Provide a complete, detailed mechanism for the reaction CH;CH,OH shown here.arrow_forwardPlease draw out the whole mechanism for the following reaction.arrow_forwardDraw the complete, detailed mechanism for the reaction shown here, and explain why nucleophilic attack takes place predominantly at the epoxide carbon that is attached to the vinyl group. HCI H,0 ОН 63%arrow_forward
- Draw the detailed mechanism and the product for the following reaction. Be sure to include stereochemistry, if applicable. Brarrow_forwardDraw a complete, detailed mechanism for the following reaction. A key intermediate is provided.arrow_forwardPlease draw the mechanism of the reaction shown below.arrow_forward
- Draw a complete, detailed mechanism for the reaction shown here.arrow_forwardDraw the complete, detailed mechanism for the reaction shown here and, using the mechanism, predict the major product. TSOH is a strong acid. -NH2 НО ? TSOH, C6H6, Aarrow_forwarda) Draw a complete, detailed mechanism for the following reaction and label the rate- determining step. H,SO, b) Show how the following molecule can be synthesized from benzene ZEU-arrow_forward
- ChemistryChemistryISBN:9781305957404Author:Steven S. Zumdahl, Susan A. Zumdahl, Donald J. DeCostePublisher:Cengage LearningChemistryChemistryISBN:9781259911156Author:Raymond Chang Dr., Jason Overby ProfessorPublisher:McGraw-Hill EducationPrinciples of Instrumental AnalysisChemistryISBN:9781305577213Author:Douglas A. Skoog, F. James Holler, Stanley R. CrouchPublisher:Cengage Learning
- Organic ChemistryChemistryISBN:9780078021558Author:Janice Gorzynski Smith Dr.Publisher:McGraw-Hill EducationChemistry: Principles and ReactionsChemistryISBN:9781305079373Author:William L. Masterton, Cecile N. HurleyPublisher:Cengage LearningElementary Principles of Chemical Processes, Bind...ChemistryISBN:9781118431221Author:Richard M. Felder, Ronald W. Rousseau, Lisa G. BullardPublisher:WILEY