Microbiology: An Introduction
12th Edition
ISBN: 9780321929150
Author: Gerard J. Tortora, Berdell R. Funke, Christine L. Case
Publisher: PEARSON
expand_more
expand_more
format_list_bulleted
Concept explainers
Videos
Question
Chapter 16, Problem 9MCQ
Summary Introduction
Introduction:
Interferon’s (IFNs) are the antiviral agents which is first discovered in 1957 by Alick Isaacs and Jean Lindenmann. Interferons are cytokines, which involve in cellular signaling between the cells to provide the immune response to the cells from the viral infections.
Interferon’s (IFNs) are antiviral proteins, which show the defense activities against the various viral infections without damaging the body cells. However, the IFNs also play a major role against some acute infections such as influenza and colds. There are three types of interferon’s, which includes,
-
- 1. Alpha interferon (IFN-α)
- 2. Beta interferon (IFN-β)
- 3. Gamma interferon (IFN-γ)
Expert Solution & Answer
Want to see the full answer?
Check out a sample textbook solution
Students have asked these similar questions
A researcher performs an experiment where he infects 2 mice (Mouse A and Mouse B) with herpes simplex virus (HSV). To measure the cytotoxicity of CD8+ T cells from Mouse A, he isolates CD8+ T cells from Mouse A and co-cultures them with a mixture of HSV-infected spleen cells from Mouse B. A day later, he checks the co-culture, but none of the infected spleen cells from Mouse B have been killed.
What could explain this observation?
a.Mouse B does not express the invariant chain (Ii)
b.Mouse A and Mouse B express different MHC alleles
c.Mouse A does not express TLR2/6
d.HSV immunoevasins block MHC-II expression
Explain why each choice (a-d) is correct or incorrect.
Allergens differ from antigens because
a. Allergens produce an abnormally large immune response to what is an otherwise harmless particle.
b. Allergens do not involve the leucocytes, they simple stimulate the inflammatory response.
c. Allergens are only active seasonally and are generally harmless to the body.
d. Allergens are primarily plant derived while antigens are bacterial or viral in nature.
Identify the mismatched pair.
a. CXCR4: lymphocyte tropic
b. exogenous retrovirus: originates outside host’s body
c. infectious virion production: activated CD4 T cells
d. tat: controls export of transcripts from the nucleus
e. lentivirus: long incubation period
f. CCR5: macrophage tropic.
Chapter 16 Solutions
Microbiology: An Introduction
Ch. 16 - Identify at least one physical and one chemical...Ch. 16 - Define inflammation, and list its characteristics.Ch. 16 - What are interferons? Discuss their roles in...Ch. 16 - How can the complement system cause endotoxic...Ch. 16 - Patients with X-linked chronic granulomatous...Ch. 16 - Prob. 6RCh. 16 - Give several examples of how microbes evade the...Ch. 16 - Prob. 8RCh. 16 - Are the following involved in innate or adaptive...Ch. 16 - These agranulocytes are not phagocytic until they...
Ch. 16 - Prob. 1MCQCh. 16 - Prob. 2MCQCh. 16 - If the following are placed in the order of...Ch. 16 - Prob. 4MCQCh. 16 - A human host can prevent a pathogen from getting...Ch. 16 - Prob. 6MCQCh. 16 - In 1884. Elie Metchnikoff observed blood cells...Ch. 16 - Prob. 8MCQCh. 16 - Prob. 9MCQCh. 16 - Prob. 10MCQCh. 16 - Prob. 1ACh. 16 - Prob. 2ACh. 16 - Prob. 3ACh. 16 - The list below identifies a virulence factor for a...Ch. 16 - People with Rhinovirus infections of the nose and...Ch. 16 - Prob. 2CAECh. 16 - Leukocyte adherence deficiency (LAD) is an...Ch. 16 - The neutrophils of individuals with Chdiak-Higashi...Ch. 16 - Consider the following. a. In laboratory...
Knowledge Booster
Learn more about
Need a deep-dive on the concept behind this application? Look no further. Learn more about this topic, biology and related others by exploring similar questions and additional content below.Similar questions
- A young child is hospitalized with recurring bacterial infections, although she appears to make normal responses to viruses. Which of the following molecules might be defective in her immune system? (select all that could contribute to this condition) Select one or more: a.RAG1/RAG2 b.MCP or DAF c.C3 d.CXCL-8 e.IFN receptorsarrow_forwardIdentify the statement that does not provide accurate evidence as to why HIV is so lethal. a. During the course of infection, HIV increases immune activation by altering intestinal physiology to let more microbes into the blood supply. b. Immune evasion increases in many infections due to HIV virions evolving new and unrecognizable epitopes (antigens). c. In many individuals the virus population evolves to use different receptors to gain access to a greater diversity of host immune cells. d. HIV causes enhanced replication and proliferation of T cells, which allows the immune system to work better at defending against pathogens.arrow_forwardUsing the AAV virus you created in the simulation, you introduce it to a mouse model for heart failure to determine the effect of SERCA2A in heart failure. a. Why would this virus only affect the myocardium and not other cell types within the mouse? b. Would the mouse then be able to spread that virus to other mice? Explain.arrow_forward
- All of the following statements about polioviruses are correct except _____. a. Poliovirus vaccines are produced in both inactivated and live-attenuated forms. b. The oral poliovirus vaccine is composed of three liveattenuated viral strains. c. Poliovirus infects both humans and cattle. d. If genetic reversion of strain 3 occurs when the virus is replicating in vaccinated people, pathogenesis may occur. e. In the United States, the recommended vaccine for poliovirus is the inactivated poliovirus vaccine (IPV).arrow_forwardWhich one of the following most correctly describes vaccines containing live, attenuated pathogens? A.They are administered by injection. B.They provide little cell-mediated immunity. C.There is no possibility for reversion to pathogenic form. D.Pathogen does not multiply in human hosts E.They provide extended, sometimes life-long immunity.arrow_forwardWhich of the following statements is true? A. Hypersensitivity requires previous exposure to an antigen B. Hypersensitivity is due to the presence of a virus. C. Hypersensitivity occurs in the absence of an antigen. D. Hypersensitivity is synonymous with the term " infection". E. Hypersensitivity occurs when an individual is exposed to an allergen for the first time.arrow_forward
- Complement must be inactivated because if it were NOT, A. protein synthesis would be inhibited, thus halting important cell processes. В. necessary interferons would not be produced. C. viruses could continue to multiply inside host cells using the host's own metabolic machinery. D. it could make holes in the body's own cells.arrow_forwardPrior to entry, the _________ glycoprotein of the HIV virus recognizes the ______ receptor on the surface of the macrophage. a. CCR5; gp120 b. CXCR4; CCR5 c. CD4; CCR5 d. gp120; CD4arrow_forwardUpon further testing, it is found that Matthew in question 4 does have normal cellular immunity. However, without antibodies Matthew will be less able to a. destroy cancer cells. b. destroy virus-infected cells. c. bind viral particles. d. destroy intracellular pathogens.arrow_forward
- Which of the following statements regarding CD4 is incorrect? a. MHC class II molecules present antigens to CD4 T cells. b. CD4 is the receptor used for HIV entry into CD4 T cells. c. CD4 is made up of two separate membrane-bound chains. d. Late in the progression of an HIV infection, the number of CD4 T cells in the circulation diminishes. e. CD4 is referred to as a T-cell co-receptor.arrow_forwardDecreasing the amount of cytokine produced by the body would most directly prevent what event during the progression of COVID-19 in its host? A). Early viral infection of host cells. B). Replication of infected cells. C). Excessive damage to lung cells by the hot immune system. D). Transmission of the virus from one host to another.arrow_forwardWhich of the following does not contribute to generating the diversity of antigen-binding specificities among immunoglobulins? a. somatic hypermutation b. random combination of heavy and light chains c. somatic recombination d. activation-induced cytidine deaminase (AID) e. alternative splicing of heavy-chain RNA transcripts.arrow_forward
arrow_back_ios
SEE MORE QUESTIONS
arrow_forward_ios
Recommended textbooks for you
Human Anatomy & Physiology (11th Edition)BiologyISBN:9780134580999Author:Elaine N. Marieb, Katja N. HoehnPublisher:PEARSON
Biology 2eBiologyISBN:9781947172517Author:Matthew Douglas, Jung Choi, Mary Ann ClarkPublisher:OpenStax
Anatomy & PhysiologyBiologyISBN:9781259398629Author:McKinley, Michael P., O'loughlin, Valerie Dean, Bidle, Theresa StouterPublisher:Mcgraw Hill Education,
Molecular Biology of the Cell (Sixth Edition)BiologyISBN:9780815344322Author:Bruce Alberts, Alexander D. Johnson, Julian Lewis, David Morgan, Martin Raff, Keith Roberts, Peter WalterPublisher:W. W. Norton & Company
Laboratory Manual For Human Anatomy & PhysiologyBiologyISBN:9781260159363Author:Martin, Terry R., Prentice-craver, CynthiaPublisher:McGraw-Hill Publishing Co.
Inquiry Into Life (16th Edition)BiologyISBN:9781260231700Author:Sylvia S. Mader, Michael WindelspechtPublisher:McGraw Hill Education
Human Anatomy & Physiology (11th Edition)
Biology
ISBN:9780134580999
Author:Elaine N. Marieb, Katja N. Hoehn
Publisher:PEARSON
Biology 2e
Biology
ISBN:9781947172517
Author:Matthew Douglas, Jung Choi, Mary Ann Clark
Publisher:OpenStax
Anatomy & Physiology
Biology
ISBN:9781259398629
Author:McKinley, Michael P., O'loughlin, Valerie Dean, Bidle, Theresa Stouter
Publisher:Mcgraw Hill Education,
Molecular Biology of the Cell (Sixth Edition)
Biology
ISBN:9780815344322
Author:Bruce Alberts, Alexander D. Johnson, Julian Lewis, David Morgan, Martin Raff, Keith Roberts, Peter Walter
Publisher:W. W. Norton & Company
Laboratory Manual For Human Anatomy & Physiology
Biology
ISBN:9781260159363
Author:Martin, Terry R., Prentice-craver, Cynthia
Publisher:McGraw-Hill Publishing Co.
Inquiry Into Life (16th Edition)
Biology
ISBN:9781260231700
Author:Sylvia S. Mader, Michael Windelspecht
Publisher:McGraw Hill Education
What Is A Virus ? ; Author: Peekaboo Kidz;https://www.youtube.com/watch?v=YS7vsBgWszI;License: Standard YouTube License, CC-BY