Microbiology: An Introduction
Microbiology: An Introduction
12th Edition
ISBN: 9780321929150
Author: Gerard J. Tortora, Berdell R. Funke, Christine L. Case
Publisher: PEARSON
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Chapter 16, Problem 5MCQ

A human host can prevent a pathogen from getting enough iron by all of the following except

  1. a. reducing dietary intake of iron.
  2. b. binding iron with transferrin.
  3. c. binding iron with hemoglobin.
  4. d. binding iron with ferritin.
  5. e. binding iron with siderophores.
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Virus infections induce production of interferons that act on infected cells to enhance their recognition by CD8 cytotoxic T cells. To counter these mechanisms, viruses often encode proteins that interfere with antigen processing and presentation. In an experiment, cells infected with Virus X are treated with interferon and compared with uninfected cells treated with interferon. Proteasomes are isolated from the two cell populations and their enzymatic activities are compared. The data in figure below show the amino acid preferences for cleavage of peptides by the two samples of proteasomes. Based on these data, Virus X most likely encodes a protein that interferes with: The expression of MHC class I on the surface of the infected cell The rate at which peptides are produced from intact proteins in the infected cell The transport of peptides from the cytosol to the endoplasmic reticulum in the infected cell The replacement of constitutive proteasome subunits with immunoproteasome…
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