To identify the heme degradation product (1) bilirubin, (2) biliverdin, (3) stercobilin, and (4) urobilin formed at the same time CO is produced. Concept introduction: Hemoglobin is a heme protein present in the red blood cells. The protein part is called globin and the non-protein part is heme. Heme is the prosthetic group that contains 4 pyrrole groups bonded together and has an iron atom in the center. The structure of the heme group is: The first step of degradation of heme involves opening of pyrrole ring with the release of the iron atom and production of biliverdin. The iron atom released becomes part of ferritin protein. Biliverdin produced is converted bilirubin in the spleen. Bilirubin is then transported to the liver where attachment of sugar residues to the propionate side chains of the bilirubin occurs to make it more soluble. Then more solubilized bilirubin is excreted in bile and finally to the small intestine. In the small intestine, it is converted into stercobilin for excretion in feces or urobilin for excretion in urine.

Question

3. Synthesize the following synthon from the indicated starting material. i HO.

Answer 1

Question

Chapter 15, Problem 15.101EP

(a)

Interpretation Introduction

Interpretation: To identify the heme degradation product (1) bilirubin, (2) biliverdin, (3) stercobilin, and (4) urobilin formed at the same time CO is produced.

Concept introduction: Hemoglobin is a heme protein present in the red blood cells. The protein part is called globin and the non-protein part is heme. Heme is the prosthetic group that contains 4 pyrrole groups bonded together and has an iron atom in the center. The structure of the heme group is:

The first step of degradation of heme involves opening of pyrrole ring with the release of the iron atom and production of biliverdin. The iron atom released becomes part of ferritin protein. Biliverdin produced is converted bilirubin in the spleen. Bilirubin is then transported to the liver where attachment of sugar residues to the propionate side chains of the bilirubin occurs to make it more soluble. Then more solubilized bilirubin is excreted in bile and finally to the small intestine. In the small intestine, it is converted into stercobilin for excretion in feces or urobilin for excretion in urine.

(b)

Interpretation Introduction

Interpretation: To identify the heme degradation product (1) bilirubin, (2) biliverdin, (3) stercobilin, and (4) urobilin associated with the condition called jaundice.

Concept introduction: Hemoglobin is a heme protein present in the red blood cells. The protein part is called globin and the non-protein part is heme. Heme is the prosthetic group that contains 4 pyrrole groups bonded together and has an iron atom in the center.

The structure of the heme group is:

The first step of degradation of heme involves opening of pyrrole ring with the release of the iron atom and production of biliverdin. The iron atom released becomes part of ferritin protein. Biliverdin produced is converted bilirubin in the spleen. Bilirubin is then transported to the liver where attachment of sugar residues to the propionate side chains of the bilirubin occurs to make it more soluble. Then more solubilized bilirubin is excreted in bile and finally to the small intestine. In the small intestine, it is converted into stercobilin for excretion in feces or urobilin for excretion in urine.

(c)

Interpretation Introduction

Interpretation: To identify the heme degradation product (1) bilirubin, (2) biliverdin, (3) stercobilin, and (4) urobilin for which molecular oxygen is used as a reactant.

Concept introduction: Hemoglobin is a heme protein present in the red blood cells. The protein part is called globin and the non-protein part is heme. Heme is the prosthetic group that contains 4 pyrrole groups bonded together and has an iron atom in the center.

The structure of the heme group is:

The first step of degradation of heme involves opening of pyrrole ring with the release of the iron atom and production of biliverdin. The iron atom released becomes part of ferritin protein. Biliverdin produced is converted bilirubin in the spleen. Bilirubin is then transported to the liver where attachment of sugar residues to the propionate side chains of the bilirubin occurs to make it more soluble. Then more solubilized bilirubin is excreted in bile and finally to the small intestine. In the small intestine, it is converted into stercobilin for excretion in feces or urobilin for excretion in urine.

(d)

Interpretation Introduction

Interpretation: To identify the heme degradation product (1) bilirubin, (2) biliverdin, (3) stercobilin, and (4) urobilin which is bile pigment and has a brownish color.

Concept introduction: Hemoglobin is a heme protein present in the red blood cells. The protein part is called globin and the non-protein part is heme. Heme is the prosthetic group that contains 4 pyrrole groups bonded together and has an iron atom in the center.

The structure of the heme group is:

The first step of degradation of heme involves opening of pyrrole ring with the release of the iron atom and production of biliverdin. The iron atom released becomes part of ferritin protein. Biliverdin produced is converted bilirubin in the spleen. Bilirubin is then transported to the liver where attachment of sugar residues to the propionate side chains of the bilirubin occurs to make it more soluble. Then more solubilized bilirubin is excreted in bile and finally to the small intestine. In the small intestine, it is converted into stercobilin for excretion in feces or urobilin for excretion in urine.

Bile pigments are the colored degradation product of tetrapyrrole carbon arrangement of heme portion of hemoglobin. These are excreted in bile and give characteristic color to urine and feces.

Expert Solution & Answer

Trending nowThis is a popular solution!

See solution

Check out sample textbook solution

Students have asked these similar questions

3. Synthesize the following synthon from the indicated starting material. i HO.

Identifying the stereochemistry of natural Write the complete common (not IUPAC) name of each molecule below. Note: if a molecule is one of a pair of enantiomers, be sure you start its name with D- or L- so we know which enantiomer it is. molecule H O-C-CH2 H3N. HN N H C=O common name (not the IUPAC name) NH3 ☐ H3N H ☐ CH2 X

> Draw the structure of alanine at pH 1.2. Click and drag to start drawing a structure.

Answer 2

Question

Chapter 15, Problem 15.101EP

(a)

Interpretation Introduction

Interpretation: To identify the heme degradation product (1) bilirubin, (2) biliverdin, (3) stercobilin, and (4) urobilin formed at the same time CO is produced.

Concept introduction: Hemoglobin is a heme protein present in the red blood cells. The protein part is called globin and the non-protein part is heme. Heme is the prosthetic group that contains 4 pyrrole groups bonded together and has an iron atom in the center. The structure of the heme group is:

The first step of degradation of heme involves opening of pyrrole ring with the release of the iron atom and production of biliverdin. The iron atom released becomes part of ferritin protein. Biliverdin produced is converted bilirubin in the spleen. Bilirubin is then transported to the liver where attachment of sugar residues to the propionate side chains of the bilirubin occurs to make it more soluble. Then more solubilized bilirubin is excreted in bile and finally to the small intestine. In the small intestine, it is converted into stercobilin for excretion in feces or urobilin for excretion in urine.

(b)

Interpretation Introduction

Interpretation: To identify the heme degradation product (1) bilirubin, (2) biliverdin, (3) stercobilin, and (4) urobilin associated with the condition called jaundice.

Concept introduction: Hemoglobin is a heme protein present in the red blood cells. The protein part is called globin and the non-protein part is heme. Heme is the prosthetic group that contains 4 pyrrole groups bonded together and has an iron atom in the center.

The structure of the heme group is:

The first step of degradation of heme involves opening of pyrrole ring with the release of the iron atom and production of biliverdin. The iron atom released becomes part of ferritin protein. Biliverdin produced is converted bilirubin in the spleen. Bilirubin is then transported to the liver where attachment of sugar residues to the propionate side chains of the bilirubin occurs to make it more soluble. Then more solubilized bilirubin is excreted in bile and finally to the small intestine. In the small intestine, it is converted into stercobilin for excretion in feces or urobilin for excretion in urine.

(c)

Interpretation Introduction

Interpretation: To identify the heme degradation product (1) bilirubin, (2) biliverdin, (3) stercobilin, and (4) urobilin for which molecular oxygen is used as a reactant.

Concept introduction: Hemoglobin is a heme protein present in the red blood cells. The protein part is called globin and the non-protein part is heme. Heme is the prosthetic group that contains 4 pyrrole groups bonded together and has an iron atom in the center.

The structure of the heme group is:

The first step of degradation of heme involves opening of pyrrole ring with the release of the iron atom and production of biliverdin. The iron atom released becomes part of ferritin protein. Biliverdin produced is converted bilirubin in the spleen. Bilirubin is then transported to the liver where attachment of sugar residues to the propionate side chains of the bilirubin occurs to make it more soluble. Then more solubilized bilirubin is excreted in bile and finally to the small intestine. In the small intestine, it is converted into stercobilin for excretion in feces or urobilin for excretion in urine.

(d)

Interpretation Introduction

Interpretation: To identify the heme degradation product (1) bilirubin, (2) biliverdin, (3) stercobilin, and (4) urobilin which is bile pigment and has a brownish color.

Concept introduction: Hemoglobin is a heme protein present in the red blood cells. The protein part is called globin and the non-protein part is heme. Heme is the prosthetic group that contains 4 pyrrole groups bonded together and has an iron atom in the center.

The structure of the heme group is:

The first step of degradation of heme involves opening of pyrrole ring with the release of the iron atom and production of biliverdin. The iron atom released becomes part of ferritin protein. Biliverdin produced is converted bilirubin in the spleen. Bilirubin is then transported to the liver where attachment of sugar residues to the propionate side chains of the bilirubin occurs to make it more soluble. Then more solubilized bilirubin is excreted in bile and finally to the small intestine. In the small intestine, it is converted into stercobilin for excretion in feces or urobilin for excretion in urine.

Bile pigments are the colored degradation product of tetrapyrrole carbon arrangement of heme portion of hemoglobin. These are excreted in bile and give characteristic color to urine and feces.

Expert Solution & Answer

Trending nowThis is a popular solution!

See solution

Check out sample textbook solution

Answer 3

Question

Chapter 15, Problem 15.101EP

(a)

Interpretation Introduction

Interpretation: To identify the heme degradation product (1) bilirubin, (2) biliverdin, (3) stercobilin, and (4) urobilin formed at the same time CO is produced.

Concept introduction: Hemoglobin is a heme protein present in the red blood cells. The protein part is called globin and the non-protein part is heme. Heme is the prosthetic group that contains 4 pyrrole groups bonded together and has an iron atom in the center. The structure of the heme group is:

The first step of degradation of heme involves opening of pyrrole ring with the release of the iron atom and production of biliverdin. The iron atom released becomes part of ferritin protein. Biliverdin produced is converted bilirubin in the spleen. Bilirubin is then transported to the liver where attachment of sugar residues to the propionate side chains of the bilirubin occurs to make it more soluble. Then more solubilized bilirubin is excreted in bile and finally to the small intestine. In the small intestine, it is converted into stercobilin for excretion in feces or urobilin for excretion in urine.

(b)

Interpretation Introduction

Interpretation: To identify the heme degradation product (1) bilirubin, (2) biliverdin, (3) stercobilin, and (4) urobilin associated with the condition called jaundice.

Concept introduction: Hemoglobin is a heme protein present in the red blood cells. The protein part is called globin and the non-protein part is heme. Heme is the prosthetic group that contains 4 pyrrole groups bonded together and has an iron atom in the center.

The structure of the heme group is:

The first step of degradation of heme involves opening of pyrrole ring with the release of the iron atom and production of biliverdin. The iron atom released becomes part of ferritin protein. Biliverdin produced is converted bilirubin in the spleen. Bilirubin is then transported to the liver where attachment of sugar residues to the propionate side chains of the bilirubin occurs to make it more soluble. Then more solubilized bilirubin is excreted in bile and finally to the small intestine. In the small intestine, it is converted into stercobilin for excretion in feces or urobilin for excretion in urine.

(c)

Interpretation Introduction

Interpretation: To identify the heme degradation product (1) bilirubin, (2) biliverdin, (3) stercobilin, and (4) urobilin for which molecular oxygen is used as a reactant.

Concept introduction: Hemoglobin is a heme protein present in the red blood cells. The protein part is called globin and the non-protein part is heme. Heme is the prosthetic group that contains 4 pyrrole groups bonded together and has an iron atom in the center.

The structure of the heme group is:

The first step of degradation of heme involves opening of pyrrole ring with the release of the iron atom and production of biliverdin. The iron atom released becomes part of ferritin protein. Biliverdin produced is converted bilirubin in the spleen. Bilirubin is then transported to the liver where attachment of sugar residues to the propionate side chains of the bilirubin occurs to make it more soluble. Then more solubilized bilirubin is excreted in bile and finally to the small intestine. In the small intestine, it is converted into stercobilin for excretion in feces or urobilin for excretion in urine.

(d)

Interpretation Introduction

Interpretation: To identify the heme degradation product (1) bilirubin, (2) biliverdin, (3) stercobilin, and (4) urobilin which is bile pigment and has a brownish color.

Concept introduction: Hemoglobin is a heme protein present in the red blood cells. The protein part is called globin and the non-protein part is heme. Heme is the prosthetic group that contains 4 pyrrole groups bonded together and has an iron atom in the center.

The structure of the heme group is:

The first step of degradation of heme involves opening of pyrrole ring with the release of the iron atom and production of biliverdin. The iron atom released becomes part of ferritin protein. Biliverdin produced is converted bilirubin in the spleen. Bilirubin is then transported to the liver where attachment of sugar residues to the propionate side chains of the bilirubin occurs to make it more soluble. Then more solubilized bilirubin is excreted in bile and finally to the small intestine. In the small intestine, it is converted into stercobilin for excretion in feces or urobilin for excretion in urine.

Bile pigments are the colored degradation product of tetrapyrrole carbon arrangement of heme portion of hemoglobin. These are excreted in bile and give characteristic color to urine and feces.

Expert Solution & Answer

Trending nowThis is a popular solution!

See solution

Check out sample textbook solution

Answer 4

Question

Chapter 15, Problem 15.101EP

(a)

Interpretation Introduction

Interpretation: To identify the heme degradation product (1) bilirubin, (2) biliverdin, (3) stercobilin, and (4) urobilin formed at the same time CO is produced.

Concept introduction: Hemoglobin is a heme protein present in the red blood cells. The protein part is called globin and the non-protein part is heme. Heme is the prosthetic group that contains 4 pyrrole groups bonded together and has an iron atom in the center. The structure of the heme group is:

The first step of degradation of heme involves opening of pyrrole ring with the release of the iron atom and production of biliverdin. The iron atom released becomes part of ferritin protein. Biliverdin produced is converted bilirubin in the spleen. Bilirubin is then transported to the liver where attachment of sugar residues to the propionate side chains of the bilirubin occurs to make it more soluble. Then more solubilized bilirubin is excreted in bile and finally to the small intestine. In the small intestine, it is converted into stercobilin for excretion in feces or urobilin for excretion in urine.

(b)

Interpretation Introduction

Interpretation: To identify the heme degradation product (1) bilirubin, (2) biliverdin, (3) stercobilin, and (4) urobilin associated with the condition called jaundice.

Concept introduction: Hemoglobin is a heme protein present in the red blood cells. The protein part is called globin and the non-protein part is heme. Heme is the prosthetic group that contains 4 pyrrole groups bonded together and has an iron atom in the center.

The structure of the heme group is:

The first step of degradation of heme involves opening of pyrrole ring with the release of the iron atom and production of biliverdin. The iron atom released becomes part of ferritin protein. Biliverdin produced is converted bilirubin in the spleen. Bilirubin is then transported to the liver where attachment of sugar residues to the propionate side chains of the bilirubin occurs to make it more soluble. Then more solubilized bilirubin is excreted in bile and finally to the small intestine. In the small intestine, it is converted into stercobilin for excretion in feces or urobilin for excretion in urine.

(c)

Interpretation Introduction

Interpretation: To identify the heme degradation product (1) bilirubin, (2) biliverdin, (3) stercobilin, and (4) urobilin for which molecular oxygen is used as a reactant.

Concept introduction: Hemoglobin is a heme protein present in the red blood cells. The protein part is called globin and the non-protein part is heme. Heme is the prosthetic group that contains 4 pyrrole groups bonded together and has an iron atom in the center.

The structure of the heme group is:

The first step of degradation of heme involves opening of pyrrole ring with the release of the iron atom and production of biliverdin. The iron atom released becomes part of ferritin protein. Biliverdin produced is converted bilirubin in the spleen. Bilirubin is then transported to the liver where attachment of sugar residues to the propionate side chains of the bilirubin occurs to make it more soluble. Then more solubilized bilirubin is excreted in bile and finally to the small intestine. In the small intestine, it is converted into stercobilin for excretion in feces or urobilin for excretion in urine.

(d)

Interpretation Introduction

Interpretation: To identify the heme degradation product (1) bilirubin, (2) biliverdin, (3) stercobilin, and (4) urobilin which is bile pigment and has a brownish color.

Concept introduction: Hemoglobin is a heme protein present in the red blood cells. The protein part is called globin and the non-protein part is heme. Heme is the prosthetic group that contains 4 pyrrole groups bonded together and has an iron atom in the center.

The structure of the heme group is:

The first step of degradation of heme involves opening of pyrrole ring with the release of the iron atom and production of biliverdin. The iron atom released becomes part of ferritin protein. Biliverdin produced is converted bilirubin in the spleen. Bilirubin is then transported to the liver where attachment of sugar residues to the propionate side chains of the bilirubin occurs to make it more soluble. Then more solubilized bilirubin is excreted in bile and finally to the small intestine. In the small intestine, it is converted into stercobilin for excretion in feces or urobilin for excretion in urine.

Bile pigments are the colored degradation product of tetrapyrrole carbon arrangement of heme portion of hemoglobin. These are excreted in bile and give characteristic color to urine and feces.

Expert Solution & Answer

Trending nowThis is a popular solution!

See solution

Check out sample textbook solution

Answer 5

Chapter 15, Problem 15.101EP

(a)

Interpretation Introduction

Interpretation: To identify the heme degradation product (1) bilirubin, (2) biliverdin, (3) stercobilin, and (4) urobilin formed at the same time CO is produced.

Concept introduction: Hemoglobin is a heme protein present in the red blood cells. The protein part is called globin and the non-protein part is heme. Heme is the prosthetic group that contains 4 pyrrole groups bonded together and has an iron atom in the center. The structure of the heme group is:

The first step of degradation of heme involves opening of pyrrole ring with the release of the iron atom and production of biliverdin. The iron atom released becomes part of ferritin protein. Biliverdin produced is converted bilirubin in the spleen. Bilirubin is then transported to the liver where attachment of sugar residues to the propionate side chains of the bilirubin occurs to make it more soluble. Then more solubilized bilirubin is excreted in bile and finally to the small intestine. In the small intestine, it is converted into stercobilin for excretion in feces or urobilin for excretion in urine.

(b)

Interpretation Introduction

Interpretation: To identify the heme degradation product (1) bilirubin, (2) biliverdin, (3) stercobilin, and (4) urobilin associated with the condition called jaundice.

Concept introduction: Hemoglobin is a heme protein present in the red blood cells. The protein part is called globin and the non-protein part is heme. Heme is the prosthetic group that contains 4 pyrrole groups bonded together and has an iron atom in the center.

The structure of the heme group is:

The first step of degradation of heme involves opening of pyrrole ring with the release of the iron atom and production of biliverdin. The iron atom released becomes part of ferritin protein. Biliverdin produced is converted bilirubin in the spleen. Bilirubin is then transported to the liver where attachment of sugar residues to the propionate side chains of the bilirubin occurs to make it more soluble. Then more solubilized bilirubin is excreted in bile and finally to the small intestine. In the small intestine, it is converted into stercobilin for excretion in feces or urobilin for excretion in urine.

(c)

Interpretation Introduction

Interpretation: To identify the heme degradation product (1) bilirubin, (2) biliverdin, (3) stercobilin, and (4) urobilin for which molecular oxygen is used as a reactant.

Concept introduction: Hemoglobin is a heme protein present in the red blood cells. The protein part is called globin and the non-protein part is heme. Heme is the prosthetic group that contains 4 pyrrole groups bonded together and has an iron atom in the center.

The structure of the heme group is:

The first step of degradation of heme involves opening of pyrrole ring with the release of the iron atom and production of biliverdin. The iron atom released becomes part of ferritin protein. Biliverdin produced is converted bilirubin in the spleen. Bilirubin is then transported to the liver where attachment of sugar residues to the propionate side chains of the bilirubin occurs to make it more soluble. Then more solubilized bilirubin is excreted in bile and finally to the small intestine. In the small intestine, it is converted into stercobilin for excretion in feces or urobilin for excretion in urine.

(d)

Interpretation Introduction

Interpretation: To identify the heme degradation product (1) bilirubin, (2) biliverdin, (3) stercobilin, and (4) urobilin which is bile pigment and has a brownish color.

Concept introduction: Hemoglobin is a heme protein present in the red blood cells. The protein part is called globin and the non-protein part is heme. Heme is the prosthetic group that contains 4 pyrrole groups bonded together and has an iron atom in the center.

The structure of the heme group is:

The first step of degradation of heme involves opening of pyrrole ring with the release of the iron atom and production of biliverdin. The iron atom released becomes part of ferritin protein. Biliverdin produced is converted bilirubin in the spleen. Bilirubin is then transported to the liver where attachment of sugar residues to the propionate side chains of the bilirubin occurs to make it more soluble. Then more solubilized bilirubin is excreted in bile and finally to the small intestine. In the small intestine, it is converted into stercobilin for excretion in feces or urobilin for excretion in urine.

Bile pigments are the colored degradation product of tetrapyrrole carbon arrangement of heme portion of hemoglobin. These are excreted in bile and give characteristic color to urine and feces.

Answer 6

Chapter 15, Problem 15.101EP

(a)

Interpretation Introduction

Interpretation: To identify the heme degradation product (1) bilirubin, (2) biliverdin, (3) stercobilin, and (4) urobilin formed at the same time CO is produced.

Concept introduction: Hemoglobin is a heme protein present in the red blood cells. The protein part is called globin and the non-protein part is heme. Heme is the prosthetic group that contains 4 pyrrole groups bonded together and has an iron atom in the center. The structure of the heme group is:

The first step of degradation of heme involves opening of pyrrole ring with the release of the iron atom and production of biliverdin. The iron atom released becomes part of ferritin protein. Biliverdin produced is converted bilirubin in the spleen. Bilirubin is then transported to the liver where attachment of sugar residues to the propionate side chains of the bilirubin occurs to make it more soluble. Then more solubilized bilirubin is excreted in bile and finally to the small intestine. In the small intestine, it is converted into stercobilin for excretion in feces or urobilin for excretion in urine.

Answer 7

Chapter 15, Problem 15.101EP

(a)

Interpretation Introduction

Interpretation: To identify the heme degradation product (1) bilirubin, (2) biliverdin, (3) stercobilin, and (4) urobilin formed at the same time CO is produced.

Concept introduction: Hemoglobin is a heme protein present in the red blood cells. The protein part is called globin and the non-protein part is heme. Heme is the prosthetic group that contains 4 pyrrole groups bonded together and has an iron atom in the center. The structure of the heme group is:

The first step of degradation of heme involves opening of pyrrole ring with the release of the iron atom and production of biliverdin. The iron atom released becomes part of ferritin protein. Biliverdin produced is converted bilirubin in the spleen. Bilirubin is then transported to the liver where attachment of sugar residues to the propionate side chains of the bilirubin occurs to make it more soluble. Then more solubilized bilirubin is excreted in bile and finally to the small intestine. In the small intestine, it is converted into stercobilin for excretion in feces or urobilin for excretion in urine.

Answer 8

(b)

Interpretation Introduction

Interpretation: To identify the heme degradation product (1) bilirubin, (2) biliverdin, (3) stercobilin, and (4) urobilin associated with the condition called jaundice.

Concept introduction: Hemoglobin is a heme protein present in the red blood cells. The protein part is called globin and the non-protein part is heme. Heme is the prosthetic group that contains 4 pyrrole groups bonded together and has an iron atom in the center.

The structure of the heme group is:

The first step of degradation of heme involves opening of pyrrole ring with the release of the iron atom and production of biliverdin. The iron atom released becomes part of ferritin protein. Biliverdin produced is converted bilirubin in the spleen. Bilirubin is then transported to the liver where attachment of sugar residues to the propionate side chains of the bilirubin occurs to make it more soluble. Then more solubilized bilirubin is excreted in bile and finally to the small intestine. In the small intestine, it is converted into stercobilin for excretion in feces or urobilin for excretion in urine.

Answer 9

(b)

Interpretation Introduction

Interpretation: To identify the heme degradation product (1) bilirubin, (2) biliverdin, (3) stercobilin, and (4) urobilin associated with the condition called jaundice.

Concept introduction: Hemoglobin is a heme protein present in the red blood cells. The protein part is called globin and the non-protein part is heme. Heme is the prosthetic group that contains 4 pyrrole groups bonded together and has an iron atom in the center.

The structure of the heme group is:

The first step of degradation of heme involves opening of pyrrole ring with the release of the iron atom and production of biliverdin. The iron atom released becomes part of ferritin protein. Biliverdin produced is converted bilirubin in the spleen. Bilirubin is then transported to the liver where attachment of sugar residues to the propionate side chains of the bilirubin occurs to make it more soluble. Then more solubilized bilirubin is excreted in bile and finally to the small intestine. In the small intestine, it is converted into stercobilin for excretion in feces or urobilin for excretion in urine.

Answer 10

(c)

Interpretation Introduction

Interpretation: To identify the heme degradation product (1) bilirubin, (2) biliverdin, (3) stercobilin, and (4) urobilin for which molecular oxygen is used as a reactant.

Concept introduction: Hemoglobin is a heme protein present in the red blood cells. The protein part is called globin and the non-protein part is heme. Heme is the prosthetic group that contains 4 pyrrole groups bonded together and has an iron atom in the center.

The structure of the heme group is:

The first step of degradation of heme involves opening of pyrrole ring with the release of the iron atom and production of biliverdin. The iron atom released becomes part of ferritin protein. Biliverdin produced is converted bilirubin in the spleen. Bilirubin is then transported to the liver where attachment of sugar residues to the propionate side chains of the bilirubin occurs to make it more soluble. Then more solubilized bilirubin is excreted in bile and finally to the small intestine. In the small intestine, it is converted into stercobilin for excretion in feces or urobilin for excretion in urine.

Answer 11

(c)

Interpretation Introduction

Interpretation: To identify the heme degradation product (1) bilirubin, (2) biliverdin, (3) stercobilin, and (4) urobilin for which molecular oxygen is used as a reactant.

Concept introduction: Hemoglobin is a heme protein present in the red blood cells. The protein part is called globin and the non-protein part is heme. Heme is the prosthetic group that contains 4 pyrrole groups bonded together and has an iron atom in the center.

The structure of the heme group is:

The first step of degradation of heme involves opening of pyrrole ring with the release of the iron atom and production of biliverdin. The iron atom released becomes part of ferritin protein. Biliverdin produced is converted bilirubin in the spleen. Bilirubin is then transported to the liver where attachment of sugar residues to the propionate side chains of the bilirubin occurs to make it more soluble. Then more solubilized bilirubin is excreted in bile and finally to the small intestine. In the small intestine, it is converted into stercobilin for excretion in feces or urobilin for excretion in urine.

Answer 12

(d)

Interpretation Introduction

Interpretation: To identify the heme degradation product (1) bilirubin, (2) biliverdin, (3) stercobilin, and (4) urobilin which is bile pigment and has a brownish color.

Concept introduction: Hemoglobin is a heme protein present in the red blood cells. The protein part is called globin and the non-protein part is heme. Heme is the prosthetic group that contains 4 pyrrole groups bonded together and has an iron atom in the center.

The structure of the heme group is:

The first step of degradation of heme involves opening of pyrrole ring with the release of the iron atom and production of biliverdin. The iron atom released becomes part of ferritin protein. Biliverdin produced is converted bilirubin in the spleen. Bilirubin is then transported to the liver where attachment of sugar residues to the propionate side chains of the bilirubin occurs to make it more soluble. Then more solubilized bilirubin is excreted in bile and finally to the small intestine. In the small intestine, it is converted into stercobilin for excretion in feces or urobilin for excretion in urine.

Bile pigments are the colored degradation product of tetrapyrrole carbon arrangement of heme portion of hemoglobin. These are excreted in bile and give characteristic color to urine and feces.

Answer 13

(d)

Interpretation Introduction

Interpretation: To identify the heme degradation product (1) bilirubin, (2) biliverdin, (3) stercobilin, and (4) urobilin which is bile pigment and has a brownish color.

Concept introduction: Hemoglobin is a heme protein present in the red blood cells. The protein part is called globin and the non-protein part is heme. Heme is the prosthetic group that contains 4 pyrrole groups bonded together and has an iron atom in the center.

The structure of the heme group is:

The first step of degradation of heme involves opening of pyrrole ring with the release of the iron atom and production of biliverdin. The iron atom released becomes part of ferritin protein. Biliverdin produced is converted bilirubin in the spleen. Bilirubin is then transported to the liver where attachment of sugar residues to the propionate side chains of the bilirubin occurs to make it more soluble. Then more solubilized bilirubin is excreted in bile and finally to the small intestine. In the small intestine, it is converted into stercobilin for excretion in feces or urobilin for excretion in urine.

Bile pigments are the colored degradation product of tetrapyrrole carbon arrangement of heme portion of hemoglobin. These are excreted in bile and give characteristic color to urine and feces.

Answer 14

Expert Solution & Answer

Answer 15

Expert Solution & Answer

Answer 16

Trending nowThis is a popular solution!

See solution

Check out sample textbook solution

Answer 17

Trending nowThis is a popular solution!

See solution

Check out sample textbook solution

Answer 18

Trending nowThis is a popular solution!

See solution

Check out sample textbook solution

Answer 19

Trending nowThis is a popular solution!

Answer 20

Trending nowThis is a popular solution!

Answer 21

Trending nowThis is a popular solution!

Answer 22

Trending now

Answer 23

This is a popular solution!

Answer 24

See solution

Check out sample textbook solution

Answer 25

Ch. 15.1 - Which of the following statements about dietary...Ch. 15.1 - Dietary protein materials as they leave the...Ch. 15.1 - Prob. 3QQ Ch. 15.1 - Which of the following is not a proteolytic...Ch. 15.2 - The dominant use for the amino acids of the amino...Ch. 15.2 - The most abundant amino acid in the amino acid...Ch. 15.2 - Prob. 3QQ Ch. 15.3 - The reactants in a transamination reaction are a....Ch. 15.3 - Prob. 2QQ Ch. 15.3 - Prob. 3QQ

Solution Summary: The author explains the structure of the heme group. Heme is the prosthetic group that contains 4 pyrrole groups bonded together and has an iron atom in the center.

Concept explainers

Chapter 15 Solutions