Genetic Analysis: An Integrated Approach (3rd Edition)
Genetic Analysis: An Integrated Approach (3rd Edition)
3rd Edition
ISBN: 9780134605173
Author: Mark F. Sanders, John L. Bowman
Publisher: PEARSON
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Chapter 14, Problem 32P

The CRISPR - Cas 9 complex directs the Cas 9 endonuclease to a specific genomic locus. If the endonuclease domain is inactivated and replaced with a transcriptional activator (or repressor) domain, what would be the functional consequence of directing such a complex to a specific chromosomal location?

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Genetic Analysis: An Integrated Approach (3rd Edition)

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