Biochemistry: Concepts and Connections (2nd Edition)
Biochemistry: Concepts and Connections (2nd Edition)
2nd Edition
ISBN: 9780134641621
Author: Dean R. Appling, Spencer J. Anthony-Cahill, Christopher K. Mathews
Publisher: PEARSON
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Chapter 13, Problem 13P
Interpretation Introduction

Interpretation:

Draw a plausible mechanism for the oxidative decarboxylation of isocitrate by isocitrate dehydrogenase.

Introduction:

The isocitrate dehydrogenase (ISD) is a biological enzyme, which consist of 2 protein subunits. In biological organisation, it exist in two forms, NAD+ linked ISD and NADP+ linked ISD. The main role of ISD is to recruit NAD+ and NADP+, which causes the conversion of isocitrate in oxalosuccinate.

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