Biochemistry: Concepts and Connections (2nd Edition)
2nd Edition
ISBN: 9780134641621
Author: Dean R. Appling, Spencer J. Anthony-Cahill, Christopher K. Mathews
Publisher: PEARSON
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Chapter 13, Problem 11P
Interpretation Introduction
Interpretation:
The mechanism for the oxidation reaction that takes place in the conversion of dihydrolipoamide to lipoamide by the E3 subunit of pyruvate dehydrogenase complex should be drawn.
Concept introduction:
The pyruvate dehydrogenase complex consists of three complexes namely E1, E2, and E3. Pyruvate dehydrogenases are exclusively found in mitochondria. The formation of acetyl CoA in mitochondria results in the generation of dihydrolipoamide (a reduced form of lipoamide).
Pictorial Representation:
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