Human Anatomy & Physiology
1st Edition
ISBN: 9780805382952
Author: Erin C. Amerman
Publisher: PEARSON
expand_more
expand_more
format_list_bulleted
Videos
Question
Chapter 11, Problem 1AYKA
Summary Introduction
To review:
The effect of the drug, neostigmine, in synaptic transmission.
The result produced by the drug, neostigmine.
Introduction:
Synaptic transmission is a fundamental process that takes place in the nervous system. The location of synaptic transmission is synapse. The exchange of chemical and electrical signals between the neurons occur in synaptic transmission. This process is instrumental to nerve conduction and is required for sensory and motor functions.
Expert Solution & Answer
Want to see the full answer?
Check out a sample textbook solution
Students have asked these similar questions
I have stimulated a neuron with dopamine for a second followed by treating it with cocaine and calcium chelating agent (which chelates out all calcium from the system making them unavailable for function), what will be the effect of such impulse on generating an action potential in the post-synaptic neuron? Will it be different if I pretreat the set of nerve cells with cocaine and calcium chelating agent followed by stimulating the neuron with dopamine? Justify your answer with proper reasoning in brief.
There are a broad range of anti-epileptic medications currently on the market, with different therapies prescribed for different
types and severities of the condition. Given what you have learned about synaptic transmission, which of the following could be a
potential therapeutic approach to prevent the spreading of neuronal excitation? (3 correct answers, select all that apply)
O A voltage-gated calcium channel blocker/inhibitor selective to glutamate-releasing neurons.
O A voltage-gated calcium channel blocker/inhibitor selective to GABA-releasing neurons.
O A glutamate receptor blocker (antagonist).
O A GABA receptor antagonist.
O A glutamate reuptake inhibitor.
O A GABA reuptake inhibitor.
Alzheimer’s disease is thought to cause a DECREASE in the amount of acetylcholine (ACH) being released into the synaptic cleft in specific parts of the brain. What would be a possible treatment for this disease? (So basically- what would be a possible way to increase the amount of ACH in the synaptic cleft?)
Chapter 11 Solutions
Human Anatomy & Physiology
Ch. 11.1 - What are the organs of the CNS?Ch. 11.1 - Prob. 2QCCh. 11.1 - Describe the sensory, integrative, and motor...Ch. 11.1 - 4. What are the differences between the somatic...Ch. 11.1 - How does the somatic motor division of the PNS...Ch. 11.2 - What are the functions of the cell body,...Ch. 11.2 - What are the structural differences between...Ch. 11.2 - What are the functional differences between...Ch. 11.2 - What are the functions of astrocytes?Ch. 11.2 - Prob. 5QC
Ch. 11.2 - Prob. 6QCCh. 11.2 - 7. What is the function of the myelin sheath?
Ch. 11.2 - How does the myelin sheath differ in the CNS and...Ch. 11.2 - Are neurons more likely to regenerate in the CNS...Ch. 11.2 - Prob. 10QCCh. 11.3 - 1. What is the resting membrane potential?
Ch. 11.3 - Prob. 2QCCh. 11.3 - What two factors generate the resting membrane...Ch. 11.3 - Prob. 4QCCh. 11.3 - Prob. 5QCCh. 11.3 - In and around the axon, where is the higher...Ch. 11.3 - What is the resting membrane potential, and what...Ch. 11.3 - Prob. 8QCCh. 11.3 - Prob. 9QCCh. 11.3 - Prob. 10QCCh. 11.3 - What takes place during the depolarization phase...Ch. 11.3 - 7. What must be reached in order for...Ch. 11.3 - 8. What takes place during the repolarization and...Ch. 11.3 - 9. What are the absolute and relative refractory...Ch. 11.3 - 10. How do local potentials and action potentials...Ch. 11.3 - Which is useful for long-distance signaling, and...Ch. 11.3 - 12. How is an action potential propagated down an...Ch. 11.3 - Prob. 18QCCh. 11.4 - What are three locations where presynaptic axons...Ch. 11.4 - Define synaptic transmission.Ch. 11.4 - Prob. 3QCCh. 11.4 - Prob. 4QCCh. 11.4 - Prob. 5QCCh. 11.4 - Prob. 6QCCh. 11.4 - Prob. 7QCCh. 11.5 - Prob. 1QCCh. 11.5 - Prob. 2QCCh. 11.5 - Prob. 3QCCh. 11.5 - Prob. 4QCCh. 11.5 - Prob. 5QCCh. 11.6 - 1. Why are neurons organized into neuronal...Ch. 11.6 - Prob. 2QCCh. 11.6 - 3. What mechanisms stabilize neural circuits?
Ch. 11 - Which of the following statements about the...Ch. 11 - 2. Regulation of heart rate, blood pressure, and...Ch. 11 - Match each type of neuroglial cell with its...Ch. 11 - Prob. 4CYRCh. 11 - Prob. 5CYRCh. 11 - Prob. 6CYRCh. 11 - 7. Fill in the blanks: The _______is the period of...Ch. 11 - With respect to the condition of action...Ch. 11 - 9. Identify the following as properties of...Ch. 11 - The trigger for exocytosis of synaptic vesicles...Ch. 11 - Match the following neurotransmitters with their...Ch. 11 - 12. Which of the following is not a method by...Ch. 11 - 13. A ________is characterized by multiple input...Ch. 11 - Mark the following statements as true or false. If...Ch. 11 -
15. Mark the following statements as true or...Ch. 11 - Sequence the following list of events of a...Ch. 11 - 16. Mark the following statements as true or...Ch. 11 - 1. A drug that blocks channels in neurons does so...Ch. 11 - Prob. 2CYUCh. 11 - What conditions must be met for an axon to...Ch. 11 - 4. Explain how an action potential is propagated...Ch. 11 - Prob. 1AYKACh. 11 - 2. During a surgical procedure, an...Ch. 11 - Albert accidentally ingests the poison...Ch. 11 - 4. Albert, the patient in question 3, takes the...Ch. 11 - Predict the effect that tetrodotoxin would have on...Ch. 11 - Explain what would happen if depolarization of the...
Knowledge Booster
Learn more about
Need a deep-dive on the concept behind this application? Look no further. Learn more about this topic, biology and related others by exploring similar questions and additional content below.Similar questions
- Given the steps shown below, which of the following is the correct sequence for transmission at a chemical synapse? 1. neurotransmitter binds with receptor 2. sodium ions rush into neuron's cytoplasm 3. action potential depolarizes the presynaptic membrane 4. ion channel opens to allow particular ion to enter cell 5. synaptic vesicles release neurotransmitter into the synaptic cleft O 1, 2, 3, 4, 5 O 5, 1, 2, 4, 3 O 2, 3, 5, 4, 1 O4, 3, 1, 2, 5 O 3, 2, 5, 1, 4arrow_forwardWhich types of patch clamp technique should be used if you want to determine if a particular compound is influencing synaptic transmission presynaptically or post synaptically?arrow_forwardThe therapeutic effect of Aricept (generic donepezil) is due toA: binding of the drug to voltage-gated sodium channels.C: the drug producing an IPSP on the postsynaptic membrane.D: the drug causing the reuptake of acetylcholine at the synapse.E: the drug maintaining higher concentrations of acetylcholine at synapsearrow_forward
- A drug belonging to the class of monoamine oxidase inhibitors has the following function: Group of answer options Increases the permeability of calcium Increases the breakdown of acetylcholine in the synaptic cleft Increases the level of acetylcholine in the synaptic cleft Increases the level of norepinephrine in the synaptic cleft Increases the breakdown of norepinephrine in the synaptic cleftarrow_forwardArrange the events that occur during synaptic transmission. Use letters A-F to denote the correct sequence. Use the diagram on the right as a clue. Example: SENDING NEURON vescJes B 1. lon channel opens Synepto SYNAPSE 1. lon channel opens 2. Neurotransmitter is released into synaptic cleft SYNAPTIC CLEFT RECEMNG NEURC4 Neurotransmitter To us 3. Vesicle fuses with plasma membrane Jon chzn nels Neurotrensmitter Feptor Neurotrensmitter broen down zna selaesed 4. Neurotransmitter binds to receptor tOnS 5. Action potential arrives 辦 6. lon channel closesarrow_forwardDepression is a condition in which sufferers may feel low mood, lack of motivation and sleep. It is caused by a lack of serotonin in the synaptic cleft of neurone pathways. Serotonin is a neurotransmitter. a) Describe how serotonin acts as a neurotransmitter. Using your understanding of synaptic transmission, explain how communication between neurones in serotonin pathways of the brain would be affected in someone with depression. b) Doctors use tubocurarine drug as an anaesthetic as it temporarily paralyses muscles. It blocks receptors at neuromuscular junctions. Why does this lead to paralysis?arrow_forward
- Selective serotonin reuptake inhibitors (SSRIs) are drugs that can alleviate symptoms of depression by blocking the reuptake of serotonin (5-HT) from the synaptic cleft, thereby increasing the amount of time that 5-HT remains active. Elevated levels of 5-HT within the synapse are associated with feelings of well-being; conversely, low levels of 5-HT are correlated with depressive symptoms. Recent studies have shown that SSRIs can also mediate their antidepressant effects by increasing brain levels of certain cytokines, including interferon gamma (IFNY). IFNY directly induces the expression of the protein p11 in neighboring neurons, which then interacts with 5-HTR4, a 5-HT transmembrane receptor. Figures 1 and 2 provide information about this interaction. 5-HTR4 protein (% of WT) expression CAMP levels (% change control) from 120T 100+ 80+ 60+ 40+ 20+ 0 MEM TOT Figure 1 5-HTR4 protein expression in plasma membrane-enriched fraction (MEM) of hippocampal lysate and in total hippocampal…arrow_forwardParkinson's Disease Parkinson's disease is neurodegenerative disorder that affects movement. Most people affected with Parkinson's disease demonstrate rigidity, slow movement, and shaking. The symptoms of Parkinson's disease occur when the cells that produce dopamine neurotransmitters die in the brain. Explain how the signal transmission at a synapse in an individual with Parkinson's disease is different than an unaffected individual. Describe the normal process of signal transmission at a synapse. Start with the arrival of an action potential at the axon terminal and include the name of the neurotransmitter that is affected by Parkinson's disease. Explain how the process is different in individuals affected with Parkinson's disease.arrow_forwardA chemical synapse is a type of synapse that occurs between two neurons and between a motor neuron and skeletal muscle fibers (i.e. at a Neuromuscular junction, NMJ). Compare and contrast the specific events that occur at chemical synapses at these two sites. Describe clearly how they are similar and how they are different, starting at the arrival of a nerve impulse at the pre-synaptic neuron and ending up with the changes observed at the postsynaptic membranes.arrow_forward
- Studies have shown that individuals with attention deficit hyperactivity disorder (ADHD) may have lower than normal amounts of dopamine and norepinephrine excitatory neurotransmitters in their synapses. Methylphenidate is one of the drugs prescribed to individuals with ADHD. It prevents the reuptake of dopamine and norepinephrine neurotransmitters from the synapses, thereby keeping these neurotransmitters in the synapses longer. Which of the following rows correctly identify the effects of methylphenidate in individuals with ADHD? Select one: a. There is an increase in the permeability of the presynaptic neuron to potassium ions. b. There is a increase in the permeability of the postsynaptic neuron to potassium ions. c. There is an increase in the permeability of the presynaptic neuron to sodium ions. d. There is a increase in the permeability of the postsynaptic neuron to sodium ions.arrow_forwardStudies have shown that individuals with attention deficit hyperactivity disorder (ADHD) may have lower than normal amounts of dopamine and norepinephrine excitatory neurotransmitters in their synapses. Methylphenidate is one of the drugs prescribed to individuals with ADHD. It prevents the reuptake of dopamine and norepinephrine neurotransmitters from the synapses, thereby keeping these neurotransmitters in the synapses longer. Which of the following rows correctly identify the effects of methylphenidate in individuals with ADHD? Select one: a. There is an increase in the permeability of the presynaptic neuron to potassium ions. b. There is a increase in the permeability of the postsynaptic neuron to potassium ions. c. There is an increase in the permeability of the presynaptic neuron to sodium ions. d. There is a increase in the permeability of the postsynaptic neuron to sodium ions.arrow_forwardThe following diagram represents a typical serotonergic synapse. Where, specifically, do antidepressants work (e.g. SSRI)? Neurotransmitter Neurotransmitter transporter Аxon Synaptic vesicle terminal Voltage- gated Ca?+ channel Synaptic cleft Receptor Postsynaptic density Dendrite Neurotransmitter Synaptic Vesicle Neurotransmitter transporter (aka Reuptake transporter) Receptor O All of the abovearrow_forward
arrow_back_ios
SEE MORE QUESTIONS
arrow_forward_ios
Recommended textbooks for you
Biology (MindTap Course List)BiologyISBN:9781337392938Author:Eldra Solomon, Charles Martin, Diana W. Martin, Linda R. BergPublisher:Cengage Learning
Biology (MindTap Course List)
Biology
ISBN:9781337392938
Author:Eldra Solomon, Charles Martin, Diana W. Martin, Linda R. Berg
Publisher:Cengage Learning
Nervous System - Get to know our nervous system a bit closer, how does it works? | Neurology; Author: FreeMedEducation;https://www.youtube.com/watch?v=6O-0CVAgaEM;License: Standard youtube license