Why would the failure of the p53 tumor supressor gene be more likely to cause cancer in a seventy year old person compared to a ten year old person?

Q: The Bcl-2 protein was initially discovered via its ability to contribute to progression of B-cells…

A: Cancer is a disease caused by abnormal cell division.

Q: How can a defect in p53 gene contribute to cancer development?

A: Cancer is an abnormal growth of cells which tend to proliferate in an uncontrolled way and, in some…

Q: Define tumor-suppressor genes. Why is a mutated single copy of a tumor-suppressor gene expected to…

A: The repeated and uncontrollable division of cells forms a large mass called the tumor. Tumors might…

Q: Explain how p53 functions as a tumor suppressor gene. How can mutations in p53 lead to cancer, and…

A: Normal cell has low level of p53 protein. When DNA damage or other stress signals may trigger p53…

Q: Which of the following statements about tumor suppressor genes is FALSE? a) Inactivation of tumor…

A: False statement about tumor suppressor genes.

Q: Why is it harder to develop a drug that targets a tumor suppressor gene compared to an oncogene…

A: Uncontrolled cell division in the cells may result into the tumor formation. Sometimes the cells may…

Q: As a certain cell went through S phase, many mistakes were made during DNA replication that could…

A: DNA is the nucleic acids present in the organisms. DNA is the deoxy ribose nucleic acid in which…

Q: Cancer cells generally have missense mutations in p53 gene, resulting in truncated p53 normally…

A: A normal cell is converted into a cancer cell when the there is deactivation of the tumor suppressor…

Q: With regard to cancer cells, which of the following are true? DA Cancer cells are clonal, meaning…

A: Ans: Cancer: It is the uncontrolled growth of cells in response to or due to mutation.

Q: Why is it important to model cancer through the generation of induced pluripotent stem cells ?…

A: Medical technology has advanced significantly over the course of many centuries. According to…

Q: Why are deaths from infection in cancer patients so common?

A: Cancer is a condition in which the cells undergoes continuous cycle without stopping and doesn’t…

Q: Why is it important to model cancer through the generation of induced pluripotent stem cells ?…

A: Genetic transformation happens when the genetic composition of an organism is transformed by the…

Q: Put a checkmark next to any of the following scenarios that would make it MORE likely that a cell…

A: Need to find all the options that produce uncontrollable cell division  and to increase chance of…

Q: Why do mutations in DNA repair genes increase the likelihood of developing cancer?

A: Deoxyribonucleic acid (DNA) is a hereditary molecule that transfers genetic information from one…

Q: Define tumor-suppressor genes. Why is a mutation in a single copy of a tumor-suppressor gene…

A: Tumor-supressor genes: Tumor-suppressor genes is defined as normal genes that will slow down the…

Q: "In the cellular regulatory pathways that control cell growth and proliferation, the products of…

A: Normal genes that are changed to become oncogenes are known as proto-oncogenes. They carry out a…

Q: How can a mutation in a tumor-suppressor gene contribute to the development of cancer?

A: Tumor-suppressor genes are like any other normal genes whose functions include slowing down cell…

Q: Explain what is fundamental aberrations in all cancer cells ?

A: Answer: Introduction: The features of chromosomal aberrations in cancers, has studied in the 15,000…

Q: What is the difference in an oncogene and tumor suppressor gene and how can each potentially lead to…

A: Cancer is group of diseases which are characterized by abnormal and unstoppable growth of cell and…

Q: b) What is one reason that it is challenging to treat cancer?

A: The uncontrolled set of cell divisions give rise to cancer cells. This happens so, when the control…

Q: How does the multistep model of cancer explain the observation that sporadic cases of retinoblastoma…

A: Disease is a sickness or illness characterized by specific symptoms and signs. Cancer is a…

Q: What would be the effect of a mutation that inactivates the p14ARF tumor suppressor upon p53…

A: p53 is known as a cellular tumor antigen 53 is a protein found in vertebrates that is responsible…

Q: What are Ras protein and p53? How can mutations in the genes for these proteins contribute to…

A: TP53 is the gene that translates the protein called tumor protein p53 which acts as a tumor…

Q: Why is the tumor microenvironment important to cancer progression?

A: Cancer progression requires metastasis which in turn is the ability of tumors to migrate within the…

Q: What are the heritable changes in cells that contribute to cancer development?

A: Introduction  Cancer is a disease when a few of the body's cells grow out of control and spread to…

Q: Why are deaths from infection in cancer patients so common?

A: Cancer is a situation in which cells continue through a continuous cycle without pausing and do not…

Q: The following are drugs that act as anti-tumor agents and are often used as part of chemotherapeutic…

A: Drug - adriomycin, target organ - intercalates between DNA base. MECHANISM OF ACTION:Doxorubicin…

Q: 1)Briefly describe three chemical factors affecting cell division. 2)Briefly describe the three…

A: We are allowed to do one question or upto three subpart of a question.  Please repost the undone…

Q: is a normal cellular gene that through a A an oncogene. OA) proto-oncogene...loss-of-function OB)…

A: An oncogene is a cancer-causing gene that has been mutated. A proto-oncogene is a type of oncogene…

Q: What is the difference between a proto-oncogene and a tumor suppressor gene?  How can mutations in…

A: Proto-oncogenes are normally switched off. But when they get activated they cause tumors. On the…