Gain-of-function mutations could contribute to cancer progression if the mutant gene is,   a) p53   b) Rb   c) cdks   d) Wee1   2. Loss-of-function mutations could contribute to cancer progression if the mutant gene is,   a) Rb   b) Ras-GEF   c) cdc25   d) cdks

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A: The uncontrollable division of cells leads to tumor formation in cancer patients. Tumors are of two…

Q: What are Tumor Markers ?

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A: Cancer is a fatal disease that has both physical and mental consequences for a person. Cancer can…

Q: The Bcl-2 protein was initially discovered via its ability to contribute to progression of B-cells…

A: Cancer is a disease caused by abnormal cell division.

Q: Why would the failure of the p53 tumor supressor gene be more likely to cause cancer in a seventy…

A: p53 is a tumor suppressor gene which regulates cell cycle.

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A: ANSWER) TRUE Hyperplastic growth is the increase in the number of cells and therefore the…

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A: Introduction Hematopoietic stem cells:- It is an immature cell that can develop into all types of…

Q: 1

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A: * mainly there are Three Stages of Cell Signaling . The first one is reception and here the signal…

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A: Two-hit hypothesis : The "two-hit" hypothesis or model was first proposed by geneticist Alfred…

Q: Which of the following statements about tumor suppressor genes is FALSE? a) Inactivation of tumor…

A: False statement about tumor suppressor genes.

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A: A normal cell is converted into a cancer cell when the there is deactivation of the tumor suppressor…

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Q: ene therapy approaches have been studied for cancer gene therapy. These approaches include? (select…

A: Cancer Cancer is a serious disease marked by an abnormal and uncontrolled cell division of cells…

Q: How can researchers pinpoint the particular driver mutations most responsible for the cancer…

A: The development of cancer is an evolutionary process at the cellular level. Several mutations…

Q: What are the normal functions of the BRCA1 tumor suppressor gene?

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Q: why EGFR play a role in CRC and other cancer?

A: EGFR : It is epidermis growth factor receptor.  CRC:  Colorectal cancer. EGFR : It is one of the…

Q: The drug vincristine, which prevents polymerization of tubulin, is used as a chemotherapeutic agent…

A: Vincristine is a chemotherapeutic medication that belongs to the vinca alkaloids family of…

Q: Which of the following mutations is MOST likely to cause cancer? A) a mutation that causes a cyclin…

A: Introduction- Cancer is a caused by the disturbances in the  controls which regulate cells and this…

Q: Characterize the differences between tumor cells and normal cells in terms of the following…

A: A. The normal cell shows contact inhibition that means when two cells get contact then the growth…

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A: Mechanism of actions of drug vincristine in cancer treatment.

Q: solving Peto’s paradox the key to cancer prevention?

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A: Each organism's DNA sequence is unique. Its base-pair sequence might vary from time to time. It is…

Q: What is/are the role/s of molecular techniques in understanding cancer? Cite some references from…

A: In cancer, cells grow abnormally. Cancer is not one disease. It is a group of diseases. The…

Q: b) What is one reason that it is challenging to treat cancer?

A: The uncontrolled set of cell divisions give rise to cancer cells. This happens so, when the control…

Q: Rb and Ink4 Cdk inhibitors are able to slow cell cycle progression. : a) True b) False

A: The cell cycle is a series of events that occur in a cell leading to its division and duplication.…

Q: Describe the seven hallmarks of cancer i) List the seven hallmarks ii) Connect each hallmark to…

A: Weinberg and Hanahan gave 6 of the hallmarks of cancer in 2000 and then added 4 additional hallmarks…

Q: Briefly outline the location, isolation , characterisation, benefits, and limitations of adult stem…

A: The definition of a stem cell is a unspecialized cell that can renew itself and, in some cases,…

Q: Somatic stem cells are best described as ...

A: Since  the cells are somatic they would not divide through out life. They are not at dysregulated.…