one question with multiple parts! 1A) If you were a cancer biologist interested in developing new drugs that will slow down cancer cell metastasis, which of the following strategies would be most effective? a)Develop an activator of mitosis b)Make Her2 protein that is more active on the surface of the cancer cells c) Develop a molecule that increases telomerase activity d) Gene therapy to add a mutated p53 gene to the cancer cells 1B) You are a genetic counsellor, and a couple comes to you with concerns that if they have a child together the child could have the X-linked recessive disease Duchene muscular dystrophy. The man has the disease whereas the woman is a carrier. Which of the following would be a true statement to tell them? a) 100% of their male offspring will likely be carriers of the recessive allele that causes the disease b) 75% of their female offspring will likely be carriers of the recessive allele that causes the disease c) 100% of their male offspring will likely have Duchene muscular dystrophy d) 25% of their female offspring will have Duchene muscular dystrophy e) 50% of their male offspring will likely have Duchene muscular dystrophy 1C) Mendel found that in garden pea plants that the traits that determine pod texture behave according to a dominant/recessive pattern in which inflated pods are dominant and constricted pods are recessive. Assume you performed crosses similar to how Mendel performed experiments where you start with true-breeding parents. If you obtain 405 inflated-pod plants in the F2 generation, approximately how many constricted-pod plants would you expect to have? a) 135 b) 540 c) 270 d) 81 e) 405
one question with multiple parts!
1A) If you were a cancer biologist interested in developing new drugs that will slow down cancer cell metastasis, which of the following strategies would be most effective?
- a)Develop an activator of mitosis
- b)Make Her2 protein that is more active on the surface of the cancer cells
- c) Develop a molecule that increases telomerase activity
- d) Gene therapy to add a mutated p53 gene to the cancer cells
1B) You are a genetic counsellor, and a couple comes to you with concerns that if they have a child together the child could have the X-linked recessive disease Duchene muscular dystrophy. The man has the disease whereas the woman is a carrier. Which of the following would be a true statement to tell them?
- a) 100% of their male offspring will likely be carriers of the recessive allele that causes the disease
- b) 75% of their female offspring will likely be carriers of the recessive allele that causes the disease
- c) 100% of their male offspring will likely have Duchene muscular dystrophy
- d) 25% of their female offspring will have Duchene muscular dystrophy
- e) 50% of their male offspring will likely have Duchene muscular dystrophy
1C) Mendel found that in garden pea plants that the traits that determine pod texture behave according to a dominant/recessive pattern in which inflated pods are dominant and constricted pods are recessive. Assume you performed crosses similar to how Mendel performed experiments where you start with true-breeding parents. If you obtain 405 inflated-pod plants in the F2 generation, approximately how many constricted-pod plants would you expect to have?
- a) 135
- b) 540
- c) 270
- d) 81
- e) 405
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