Why are there strict reminders about mixing in the inverted position and not vortexing Plasmid samples?  Will these actions affect the plamid DNA extraction?

Basic Clinical Laboratory Techniques 6E
6th Edition
ISBN:9781133893943
Author:ESTRIDGE
Publisher:ESTRIDGE
Chapter2: Basic Hematology
Section2.3: Microhematocrit
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Why are there strict reminders about mixing in the inverted position and not vortexing Plasmid samples?  Will these actions affect the plamid DNA extraction?

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