While fatty acids longer than 20 carbons are rarely found in foods, lignoceric acid (24:0) is found in a variety of tree nuts. Answer the following based on the conversion of a molecule of lignoceric acid to 8-hydroxybutyrate. (a) What are the 8-oxidation products and how many ATP are required during activation for one molecule of lignoceric acid? (b) Given the following, how many molecules of 8-hydroxybutyrate can be produced? CoA 2 2 CoA NADH NAD+ H+ OH ẞ-hydroxybutyrate (c) Based on the total NADH and FADH2 available after converting lignoceric acid into 8-hydroxybutyrate, what is the maximum yield of ATP that can be produced in the liver? Don't forget to include any ATP required for activation steps.
While fatty acids longer than 20 carbons are rarely found in foods, lignoceric acid (24:0) is found in a variety of tree nuts. Answer the following based on the conversion of a molecule of lignoceric acid to 8-hydroxybutyrate. (a) What are the 8-oxidation products and how many ATP are required during activation for one molecule of lignoceric acid? (b) Given the following, how many molecules of 8-hydroxybutyrate can be produced? CoA 2 2 CoA NADH NAD+ H+ OH ẞ-hydroxybutyrate (c) Based on the total NADH and FADH2 available after converting lignoceric acid into 8-hydroxybutyrate, what is the maximum yield of ATP that can be produced in the liver? Don't forget to include any ATP required for activation steps.
Biochemistry
6th Edition
ISBN:9781305577206
Author:Reginald H. Garrett, Charles M. Grisham
Publisher:Reginald H. Garrett, Charles M. Grisham
Chapter25: Nitrogen Acquisition And Amino Acid Metabolism
Section: Chapter Questions
Problem 22P
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