Which of the following statements best explains why the immune system can continue to make antibodies after treatment with the anti-CD20 antibody rituximab? a. New CD20-positive B cells are reconstituted so quickly that antibody concentration during and after treatment is unaffected. b. Rituximab stimulates B-cell proliferation, so for a short while after its administration there is actually an increase in antibody concentration. c. Rituximab is a mouse monoclonal antibody and therefore its Fc region is unable to bind to the surface d. Plasma cells do not express CD20 on their cell surface, and antibody production by these cells continues unhampered. e. Rituximab stimulates anti-antibody production, leading to its rapid clearance by the body.

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A: Immunoglobulins are composed of four polypeptide chains out of which two are heavy chains and two…

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Q: how HPV was used to cure cancer? a. The HPV induced a type IV hypersensitivity immune response b.…

A: Human papiloma vaccine used in prophylaxis of cervical cancer

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A: Concept used -  T cell receptors and MHC restriction    Important definitions-  MHC restriction :…

Q: Developing B cells that fail to make productive D to J heavy-chain rearrangements on both homologous…

A: B cells get matured in the bone marrow or in the lymph node. Mature B cells express antibodies on…

Q: Which of the following might explain why some individuals lack the ability to make enough T-cells?…

A: T-cells are generally one kind of lymphocyte and one of the crucial parts of white blood cells.…

Q: Which ONE of the following genes is most likely mutated in T‐cell acute lymphoblastic leukaemia?…

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Q: Which of the following can be answered by immunohistochemistry? Select all that apply. a. Whether…

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Q: Which of the following classes of oncogenes would likely be druggable with a small molecule (select…

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Q: Antibodies can have multiple mechanisms of action. The main mechanism is "flagging" a foreign body…

A: Antibodies are immunoglobulin proteins that are produced by the immune system as a result of the…

Q: Which of the following statements regarding CD4 is incorrect? a. MHC class II molecules present…

A: CD4 could be a monomeric kind I transmembrane compound protein consisting of 4 Ig-like extracellular…

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Q: 3 4 Some antibodies can be passed from mother to child during breastfeeding. What is this type of…

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Q: The five classes of immunoglobulin differ in ….   Select one: a. None of the above b. Ability to…

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Q: Which of the following events is not associated with the establishment of allelic exclusion of…

A: Answer is A.) active transcription of RAG1 and RAG2.

Q: VDJ rearrangement occurs so that: Select one: a.after a pathogen has entered the system, B cells…

A: VDJ arrangement or VDJ recombination is the specialized mechanism which takes place in developing…

Q: All of the following are properties of B-1 cells except a. They exhibit polyspecificity. b. They…

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Q: Humanized monoclonal antibodies are best described as a. antibodies made in mice in which the…

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A: Please follow step 2 for detailed explanation.

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Genomic studies

Genomic studies (genomics) is the study of the whole genome of an organism. Using bioinformatics and high-performance computing, genomic researchers examined massive amounts of deoxyribonucleic acid (DNA)-sequence data to discover variations or mutations that affect drug response, health, or disease. Genomics is a much younger discipline than genetics, having only emerged in the last few decades as a result of technological advancements in DNA sequencing and computational biology.