In cell culture experiments, purified B cells expressing IgM can be induced to switch to producing IgE by stimulating them with an antibody to CD40 (a stimulatory antibody) plus the cytokine IL-4. In an individual undergoing an immune response, these signals would normally be provided by O follicular dendritic cells in the germinal center. Oother B cells in the germinal center. O TFH cells in the germinal center. Oany CD4 T cell in the same lymph node.

Human Anatomy & Physiology (11th Edition)
11th Edition
ISBN:9780134580999
Author:Elaine N. Marieb, Katja N. Hoehn
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Chapter1: The Human Body: An Orientation
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In cell culture experiments, purified B cells expressing IgM can be induced to switch to producing IgE by stimulating them with an
antibody to CD40 (a stimulatory antibody) plus the cytokine IL-4. In an individual undergoing an immune response, these signals would
normally be provided by
follicular dendritic cells in the germinal center.
other B cells in the germinal center.
TFH cells in the germinal center.
any CD4 T cell in the same lymph node.
00
Transcribed Image Text:In cell culture experiments, purified B cells expressing IgM can be induced to switch to producing IgE by stimulating them with an antibody to CD40 (a stimulatory antibody) plus the cytokine IL-4. In an individual undergoing an immune response, these signals would normally be provided by follicular dendritic cells in the germinal center. other B cells in the germinal center. TFH cells in the germinal center. any CD4 T cell in the same lymph node. 00
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