Which of the following statements are correct about telomeres (select all that apply)? A. A total of 6 nucleotides are lost at the end of each chromsome during each replication cycle. B. Addition of telomerase to cells that have undergone breakage-fusion-bridge cycles can reverse crisis C. Shortening of telomeres prevents cells from becoming cancerous even if they have oncogenes and defective tumor suppressor genes D. All cancer cells express high levels of telomerase E. Chromosomes without telomeres tend to undergo end-to-end fusions
Which of the following statements are correct about telomeres (select all that apply)? A. A total of 6 nucleotides are lost at the end of each chromsome during each replication cycle. B. Addition of telomerase to cells that have undergone breakage-fusion-bridge cycles can reverse crisis C. Shortening of telomeres prevents cells from becoming cancerous even if they have oncogenes and defective tumor suppressor genes D. All cancer cells express high levels of telomerase E. Chromosomes without telomeres tend to undergo end-to-end fusions
Human Anatomy & Physiology (11th Edition)
11th Edition
ISBN:9780134580999
Author:Elaine N. Marieb, Katja N. Hoehn
Publisher:Elaine N. Marieb, Katja N. Hoehn
Chapter1: The Human Body: An Orientation
Section: Chapter Questions
Problem 1RQ: The correct sequence of levels forming the structural hierarchy is A. (a) organ, organ system,...
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Question
Which of the following statements are correct about telomeres (select all that apply)?
A.
A total of 6 nucleotides are lost at the end of each chromsome during each replication cycle.
B.
Addition of telomerase to cells that have undergone breakage-fusion-bridge cycles can reverse crisis
C.
Shortening of telomeres prevents cells from becoming cancerous even if they have oncogenes and defective tumor suppressor genes
D.
All cancer cells express high levels of telomerase
E.
Chromosomes without telomeres tend to undergo end-to-end fusions
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Step 1: Introduction:
Cancer is a broad cluster of diseases that is distinguished by the uncontrolled proliferation and transmission of abnormal cells. These cells possess the capability to enter and destroy healthy tissues within the organism. Neoplastic growths have the potential to manifest in any anatomical location and originate from diverse cellular lineages. Upon formation, cancerous cells have the ability to spread through adjacent tissues and travel to distant anatomical sites via the circulatory or lymphatic pathways. The phenomenon is commonly referred to as metastasis.
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