Which of the following is CORRECT?A) Pyruvate kinase requires Mg2+ for maximal activity.B) A small change of ATP concentrations within a cell leads to large changes ofAMP concentrations.C) A reduction of ATP concentrations will ultimately raise pyruvate kinaseactivity.D) All of the above.E) None of the above.

Pyruvate Kinase is an enzyme which catalyzes the last step of glycolysis, i.e. conversion of…

Answered: Which of the following is CORRECT? A)…

Biochemistry

9th Edition

ISBN:9781319114671

Author:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.

Publisher:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.

Chapter1: Biochemistry: An Evolving Science

Section: Chapter Questions

Problem 1P

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Vitamin K questionsa) What transformation of glutamate side chains is Vitamin K (as its reduced form, VitaminKH2) involved in, and what is the relevance of this reaction to blood clotting?b) How does the blood thinner Coumadin (warfarin) prevent clotting?c) How can the dietary intake of large amounts of green vegetables, such as broccoli or kaleinterfere with the action of Coumadin?
The authors in the abstract given above describe the mechanism for the activation of metallothionein (MTF) that results in the detoxification of heavy metals. Use a diagram to illustrate and describe the cascade of events that occur as proposed by the authors. Induction of metallothionein (MT) expression is involved in metal homeostasis and detoxification. To identify the key pathways that regulate metal-induced cytotoxicity, we investigate how phosphorylated metal-responsive transcription factor-1 (MTF-1) contributed to induction of MT expression. Immortal human embryonic kidney cells (HEK cells) were treated with seven kinds of metals including cadmium chloride (CdCl2), zinc sulphate (ZnSO4), copper sulphate (CuSO4), lead acetate (PbAc), nickel sulphate (NiSO4), sodium arsenite (NaAsO2), and potassium bichromate (K2Cr2O7). The MT expression was induced in a dose-response and time-dependent manner upon various metal treatments. A cycle of phosphorylation and dephosphorylation was…
For each of the following examples, indicate whether the drug is acting on physical process, chemical process or enzymatic system (your answer should be only; Physical, Chemical or Enzymatic). A. A drug is used as an antidote in lead poisoning and acts by binding to lead particles in body (chelation therapy). B. A drug acts to reduce flatulence and acts by reducing the surface tension of intestinal gas bubbles in the GI tract (e.g. Simethicone). C. A drug competes with alpha-glucosidase in intestine to reduce glucose conversion from disaccharides (e.g. Acarbose).
Q44
61. Degradation of glycogen in muscle fails to supply significant amounts of blood glucose because muscle lacks which of the following enzymes? A) Glucose-6-phosphatase B) Glucose-6-phosphate dehydrogenase C) Glycogen phosphorylase D) Phosphoglucomutase E) Phosphorylase kinase
Which of the following is NOT true of Complex 1? a.) it's a proton pump and it pumps 4H+ into the intermembrane space for every pair of electrons donated by NADH. b.) electrons from NADH are accepted by an FMN prosthetic group within Complex I. c.) electrons from NADH are passed through Complex 1 prosthetic groups to ubiquinone. d.) it accepts electrons from either NADH or FADH2
Which of these is not a component of phosphatidylcholine? a) glycerol b) phosphate c) choline d) sphingosine
Which of the following condenses acyl and malonyl groups? a) Acetyl co-A ACP transacetylase b) Malonyl co-A ACP transferase c) ß-ketoacyl ACP synthase d) Acyl carrier protein
Which of the following statements is/are CORRECT? OA) Phosphoenolpyruvate carboxykinase is inhibited by ADP. B) Pyruvate carboxylase is inhibited by ADP. C) Fructose-1,6-bisphosphatase is inhibited by ADP. OD) A and B. OE) B and C. 4
Glucose-6- phosphatase catalyzes the following reaction: glucose – 6-phosphate + H2O = glucose + phosphate. Glucose-6- phosphatase would be classified as a(n) a) kinase b) hydrolase c) lyase d) oxidoreductase If ∆G for a biochemical reaction has a positive value, this means: a) the reaction will proceed very rapidly b) the reaction will proceed very slowly c) the reaction will generate heat d) The reaction requires energy input to proceed. Which thermodynamic parameter do enzymes change? A) entropy b) activation energy c) enthalpy d) all of these Enzymes have which effect on the chemical equilibrium of a biochemical reaction? A) the equilibrium shifts to favor products b) the equilibrium shifts to favor reactants c) The equilibrium does not shift, but gets there faster d) a new equilibrium is formed

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