Homework Help is Here – Start Your Trial Now!
Science
Biology
A mutation in the alpha globin gene that introduced one additional basic amino acid residue in the BPG binding pocket would: (select one)

A mutation in the alpha globin gene that introduced one additional basic amino acid residue in the BPG binding pocket would: (select one)

Human Anatomy & Physiology (11th Edition)
Human Anatomy & Physiology (11th Edition)
11th Edition
ISBN:9780134580999
Author:Elaine N. Marieb, Katja N. Hoehn
Publisher:Elaine N. Marieb, Katja N. Hoehn
Chapter1: The Human Body: An Orientation
Section: Chapter Questions
Problem 1RQ: The correct sequence of levels forming the structural hierarchy is A. (a) organ, organ system,...
See similar textbooks
icon
Related questions
Question

A mutation in the alpha globin gene that introduced one additional basic amino acid residue in the BPG binding pocket would: (select one)

a) Eliminate Hb’s positive cooperativity.

b) Decrease Hb’s O2 binding affinity.

c) Increase Hb’s O2 binding affinity.

d) Increase O2 binding in muscle and decrease it in lungs.

e) Decrease O2 binding in muscle and increase it in lungs.

f) It would have no effect on the adult form of Hb.

Expert Solution
Step 1

2,3-Bisphosphoglycerate or BPG shifts T-R equilibrium to the left as it only binds to deoxyhemoglobin. 

In normal conditions, binding of BPG to hemoglobin decreases the oxygen binding affinity. 

steps

Step by step

Solved in 4 steps

SEE SOLUTIONCheck out a sample Q&A here
Blurred answer
Similar questions
  • SEE MORE QUESTIONS
Recommended textbooks for you
Human Anatomy & Physiology (11th Edition)
Human Anatomy & Physiology (11th Edition)
Biology
ISBN:
9780134580999
Author:
Elaine N. Marieb, Katja N. Hoehn
Publisher:
PEARSON
Biology 2e
Biology 2e
Biology
ISBN:
9781947172517
Author:
Matthew Douglas, Jung Choi, Mary Ann Clark
Publisher:
OpenStax
Anatomy & Physiology
Anatomy & Physiology
Biology
ISBN:
9781259398629
Author:
McKinley, Michael P., O'loughlin, Valerie Dean, Bidle, Theresa Stouter
Publisher:
Mcgraw Hill Education,
Molecular Biology of the Cell (Sixth Edition)
Molecular Biology of the Cell (Sixth Edition)
Biology
ISBN:
9780815344322
Author:
Bruce Alberts, Alexander D. Johnson, Julian Lewis, David Morgan, Martin Raff, Keith Roberts, Peter Walter
Publisher:
W. W. Norton & Company
Laboratory Manual For Human Anatomy & Physiology
Laboratory Manual For Human Anatomy & Physiology
Biology
ISBN:
9781260159363
Author:
Martin, Terry R., Prentice-craver, Cynthia
Publisher:
McGraw-Hill Publishing Co.
Inquiry Into Life (16th Edition)
Inquiry Into Life (16th Edition)
Biology
ISBN:
9781260231700
Author:
Sylvia S. Mader, Michael Windelspecht
Publisher:
McGraw Hill Education
SEE MORE TEXTBOOKS