1) Individual with the genetic disease of Familial hypercholesterolemia have higher levels of cholesterol in the blood, which of the following could cause this disease: (A)   deregulated biosynthesis of low-density lipoprotein (LDL) receptors (B)    high dietary cholesterol (C)    plaque formation in the arteries. (D)   high cholesterol biosynthesis in liver tissue. (E)    deregulated biosynthesis of low-density lipoprotein (LDL)  2) The enzyme inorganic pyrophosphatase utilizes ____ as its substrate.            A). ATP            B). ADP            C). AMP            D). PPi            E). phosphate

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Nitrogen metabolism

Nitrogen metabolism is the synthesis, utilization or uptake, breakdown, and excretion of nitrogenous compounds in the body. The nitrogen metabolism encompasses nitrogen fixation, biosynthesis, and the breakdown of amino acids, purines, and pyrimidine. Since nitrogen-containing compounds are required for various life processes, nitrogen is an important element of life.