A patient with chronic pancreatitis and hence decreased secretory function of pancreas was prescribed an enzymatic drug «Enzystal» before each meal. Explain this prescription. For that: a)Name pansreatic enzymes, participating in digestion of carbohydrates, lipids and proteins. What is their pH optimum and how is it reached in duodenum? b) Draw the scheme representing the cascade of activation of pancreatic proteolytic enzymes. Indicate the mechanism ofactivation and its reversability c)Why are proteolytic enzymes secreted by pancreas in inactive form? d)What recommendations on diet can be given to this patient?

Biochemistry
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ISBN:9781319114671
Author:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.
Publisher:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.
Chapter1: Biochemistry: An Evolving Science
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1.A patient with chronic pancreatitis and hence decreased secretory function of pancreas was prescribed an enzymatic drug «Enzystal» before each meal. Explain this prescription. For that: a)Name pansreatic enzymes, participating in digestion of carbohydrates, lipids and proteins. What is their pH optimum and how is it reached in duodenum? b) Draw the scheme representing the cascade of activation of pancreatic proteolytic enzymes. Indicate the mechanism ofactivation and its reversability c)Why are proteolytic enzymes secreted by pancreas in inactive form? d)What recommendations on diet can be given to this patient?
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