According to the “Hawaiian Punch" principle, different compartments of thesecretory and endocytic pathways are topologically equivalent to each other and tothe extracellular space.a) Explain how vesicular transport generates this topological equivalence.b) During mitosis in mammalian cells, the nuclear envelope breaks down intovesicles. Are the topological properties of the cell altered by this event? Justifyyour answer.

According to the "Hawaiin punch" principle, multiple secretory and endocytic compartment pathways…

Answered: ccording to the “Hawaiian Punch"…

Human Anatomy & Physiology (11th Edition)

11th Edition

ISBN:9780134580999

Author:Elaine N. Marieb, Katja N. Hoehn

Publisher:Elaine N. Marieb, Katja N. Hoehn

Chapter1: The Human Body: An Orientation

Section: Chapter Questions

Problem 1RQ: The correct sequence of levels forming the structural hierarchy is A. (a) organ, organ system,...

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Similar questions

1-what are the largest element of the cytoskeleton and can dynamically grow and shrink by the addition or subtraction of tubulin subunits. 2-Many less dynamic, more permanent cellular structures such as the nuclear lamina have (????) as the major cytoskeletal component Microtubules Intermediate filaments Microfilaments 3-when a ligand binds a (????) the conformation of the receptor changes, opening a selective pore. GPCR Ligand gated ion channel Ligandase pore Voltage gated ion channel
Demonstrate the listed processes
Trace the pathway of a protein embedded in the membrane from the nucleus to becoming part of the lysosome. Please number the steps in the order they occur in the cell. For full credit, you must describe each organelle and transport vesicle the product moves through and describe in detail how each organelle modifies the protein.
Trace the cytoplasmic route of a protein that the cell will utilise. Please number the steps in the cell in the order they appear. To get full credit, you must explain each organelle and transport vesicle through which the product passes, as well as how each organelle alters the protein in detail.
A hypothetical molecule X+ is important for cell function and is present outside of a cell. List the factors that that will perdominantly influence the ability of molecule X to cross the membrane and enter the cell.
The LDL receptor is internalized via endocytosis every ten minutes and recycled to the membrane. How does the cell recycle the receptor and not the ligand (in this case LDL)? A. The high pH (~10) of the early endosome causes dissociation of LDL from the receptor and the receptor is segregated into recycling endosomes. B. The low pH (~5) of the early endosome causes dissociation of LDL from the receptor and the receptor is segregated into recycling endosomes. O C. A targeting sequence on the ligand sorts it to the late endosome/lysosome. D. This is an error-prone process, the ligand often gets recycled accidentally.
Liver cells in culture were kept at 0°C and treated with trypsin to digest the receptors on the cell surface. The temperature was then raised to 37°C and radioactive LDL was added to the culture media. Several hours later, the labeled LDL was found to be inside the cells. This specific process of LDL uptake is A. active transport B. facilitated diffusion C. phagocytosis D. pinocytosis E. receptor-mediated endocytosis
1) Which of the following contains all of the information required to target a precursor protein from the cytosol to the mitochondrial matrix? a. N-terminal uptake-targeting sequence b. C-terminal uptake-targeting sequence c. post-translational organelle d. translocon e. None of the above 2) In the absence of targeting information, what is the default location of proteins synthesized on cytosolic ribosomes? a. Golgi apparatus b. ER lumun c. Cytosol d. Cell plasma membrane e. ER membrane
Biopsies from aggressive cancers often have cells that contain several nuclei per cell when viewed through a microscope. Which scenario could explain how such a multinucleated cell might have come to be? (a) The cell underwent repeated mitosis with simultaneous cytokinesis. (b) The cell had multiple S phases before it entered mitosis. (c) The cell underwent repeated mitosis, but cytokinesis did not occur. (d) The cell underwent repeated cytokinesis but no mitosis. (e) The cell actually went through meiosis and not mitosis.
The endoplasmic reticulum (ER) and Golgi apparatus are two organelles that are not physically joined, yet materials can still be exchanged between them. How can materials, such as proteins, move between the ER and Golgi when these organelles are not touching each other? A) When a substance such as a protein needs to move between these organelles, it is first dismantled in one organelle, then reassembled when it arrives at the other organelle. B) Substances such as proteins can travel between these organelles within transport vesicles. C) None of these; a single molecule will not go from one organelle to another. D) Substances like proteins will move between these organelles by diffusion through the cytoplasm. ..
Match the following structures with their definitions: (1) Golgi apparatus (2) mitochondria (3) peroxisomes (4) cilia (5) endoplasmic reticulum (6) cytoskeleton (7) vesicles (8) ribosomes A. sacs that contain enzymes thatcatalyze a variety of specific biochemical reactionsB. structures on which protein synthesis occursC. structures that house the reactions that release energy from nutrientsD. a network of microfilaments and microtubules that supports and shapes a cellE. a structure that adds sugars to certain proteins and processes them for secretionF. membrane-bounded sacsG. a network of membranous channels and sacs where lipids and proteinsare synthesizedH. hairlike structures that extend from certain cell surfaces and wave about.
4) Consider the synaptic vesicle cycle i shown below: Budding Endosome fusion NT Early endosome H+ ii iii iv Ca2+ Plasma membrane Synaptic cleft a) In your own words, describe each step highlighted below. Include key molecular events in your description: į, ii. ii. iv. V. b) Which mode of synaptic vesicle recycling is shown above?

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