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61. Degradation of glycogen in muscle fails to supply significant amounts of blood glucose because muscle lacks which of the following enzymes? A) Glucose-6-phosphatase B) Glucose-6-phosphate dehydrogenase C) Glycogen phosphorylase D) Phosphoglucomutase E) Phosphorylase kinase

61. Degradation of glycogen in muscle fails to supply significant amounts of blood glucose because muscle lacks which of the following enzymes? A) Glucose-6-phosphatase B) Glucose-6-phosphate dehydrogenase C) Glycogen phosphorylase D) Phosphoglucomutase E) Phosphorylase kinase

Human Anatomy & Physiology (11th Edition)
Human Anatomy & Physiology (11th Edition)
11th Edition
ISBN:9780134580999
Author:Elaine N. Marieb, Katja N. Hoehn
Publisher:Elaine N. Marieb, Katja N. Hoehn
Chapter1: The Human Body: An Orientation
Section: Chapter Questions
Problem 1RQ: The correct sequence of levels forming the structural hierarchy is A. (a) organ, organ system,...
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**Question 61: Degradation of Glycogen in Muscle** **Degradation of glycogen in muscle fails to supply significant amounts of blood glucose because muscle lacks which of the following enzymes?** A) Glucose-6-phosphatase B) Glucose-6-phosphate dehydrogenase C) Glycogen phosphorylase D) Phosphoglucomutase E) Phosphorylase kinase This question pertains to the biochemical processes involved in glycogen metabolism within muscle cells. Glycogen degradation in muscles primarily serves as a source of glucose for muscle energy requirements rather than supplying glucose to the bloodstream. The lack of a specific enzyme in muscle tissue prevents it from converting glycogen to free glucose that can enter the bloodstream. Understanding which enzyme is absent is critical for comprehending muscle physiology and energy metabolism. **Explanation**: - **Glucose-6-phosphatase** is the enzyme responsible for converting glucose-6-phosphate to free glucose in the liver, which can then be released into the blood. - **Glucose-6-phosphate dehydrogenase** is involved in the pentose phosphate pathway, not directly in glycogen degradation to glucose. - **Glycogen phosphorylase** is critical in the breakdown of glycogen to glucose-1-phosphate. - **Phosphoglucomutase** converts glucose-1-phosphate to glucose-6-phosphate, a step in glycogen metabolism. - **Phosphorylase kinase** activates glycogen phosphorylase, facilitating glycogen breakdown.
Transcribed Image Text:**Question 61: Degradation of Glycogen in Muscle** **Degradation of glycogen in muscle fails to supply significant amounts of blood glucose because muscle lacks which of the following enzymes?** A) Glucose-6-phosphatase B) Glucose-6-phosphate dehydrogenase C) Glycogen phosphorylase D) Phosphoglucomutase E) Phosphorylase kinase This question pertains to the biochemical processes involved in glycogen metabolism within muscle cells. Glycogen degradation in muscles primarily serves as a source of glucose for muscle energy requirements rather than supplying glucose to the bloodstream. The lack of a specific enzyme in muscle tissue prevents it from converting glycogen to free glucose that can enter the bloodstream. Understanding which enzyme is absent is critical for comprehending muscle physiology and energy metabolism. **Explanation**: - **Glucose-6-phosphatase** is the enzyme responsible for converting glucose-6-phosphate to free glucose in the liver, which can then be released into the blood. - **Glucose-6-phosphate dehydrogenase** is involved in the pentose phosphate pathway, not directly in glycogen degradation to glucose. - **Glycogen phosphorylase** is critical in the breakdown of glycogen to glucose-1-phosphate. - **Phosphoglucomutase** converts glucose-1-phosphate to glucose-6-phosphate, a step in glycogen metabolism. - **Phosphorylase kinase** activates glycogen phosphorylase, facilitating glycogen breakdown.
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