Signaling by tyrosine kinase receptors is generally associated with all of the following except: A) receptor dimerization B) growth factor responses C) heterotrimeric G proteins D) cross phosphorylation E) generating protein binding sites due to phosphorylation

Signaling by tyrosine kinase receptors is generally associated with all of the following except: A) receptor dimerization B) growth factor responses C) heterotrimeric G proteins D) cross phosphorylation E) generating protein binding sites due to phosphorylation

Biochemistry

9th Edition

ISBN:9781319114671

Author:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.

Publisher:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.

Chapter1: Biochemistry: An Evolving Science

Section: Chapter Questions

Problem 1P

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Question

Signaling by tyrosine kinase receptors is generally associated with all of the following
except:
A) receptor dimerization
B) growth factor responses
C) heterotrimeric G proteins
D) cross phosphorylation
E) generating protein binding sites due to phosphorylation

Expert Solution

Tyrosine Kinase receptor

In contrast to G protein-coupled receptors where the cytosolic domain of the receptor is close to the G-protein in the cytosol, the receptor in 'tyrosine kinase receptors' is linked to the tyrosine kinase located in the cytosol.

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