I’m having hard time if this protein is folded or unfolded can you please help? Under the stated conditions, the majority of the protein molecules insolution would beO in a roughly-equal mixture of unfolded and folded states.O unfolded.folded.O in an indeterminate mixture of folded and unfolded states. Protein foldingConsider the equilibrium between the unfolded and folded (native) statesof a protein, shown below:unfolded, inactive;collection of many,many "random"structuresfolded, native,active 3-dimensionalstructure of proteinfolding (orrenaturation)unfolding (ordenaturation)For the reaction written as shown (folding direction), for this proteinunder certain solution conditions at 25 "C:AH'fe=-25.1 kJ/molfoldingAS'folding =-0.06 kJ / (mol K).

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Answered: Under the stated conditions, the…

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Biochemistry

Under the stated conditions, the majority of the protein molecules in solution would be

Biochemistry

9th Edition

ISBN:9781319114671

Author:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.

Publisher:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.

Chapter1: Biochemistry: An Evolving Science

Section: Chapter Questions

Problem 1P

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Question

I’m having hard time if this protein is folded or unfolded can you please help?

Under the stated conditions, the majority of the protein molecules in
solution would be
O in a roughly-equal mixture of unfolded and folded states.
O unfolded.
folded.
O in an indeterminate mixture of folded and unfolded states.

Protein folding
Consider the equilibrium between the unfolded and folded (native) states
of a protein, shown below:
unfolded, inactive;
collection of many,
many "random"
structures
folded, native,
active 3-dimensional
structure of protein
folding (or
renaturation)
unfolding (or
denaturation)
For the reaction written as shown (folding direction), for this protein
under certain solution conditions at 25 "C:
AH'fe
=-25.1 kJ/mol
folding
AS'
folding =-0.06 kJ / (mol K).

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