Two proteins are discovered, and both are shown to have a potential in treating fatty liver  disease. The structural differences of the proteins require them to be delivered using  spherical nanoparticles made of different polymers. The scientists are trying to decide  which protein will be more efficient to use in applications where a faster drug release is  more favorable. Protein 1 is loaded into spherical nanoparticles made of polymer 1 which  has R=100 nm at a concentration of 50 nM. Protein 2 is loaded into spherical  nanoparticles made of polymer 2 which has R=250 nm, at a concentration of 50 nM. The  partition coefficient of polymer 1 is 0.01 and is known to be half of partition coefficient  of polymer 2. The diffusion coefficient of protein 1 in polymer 1 is 2x10-6 cm2/s, and  diffusion coefficient of protein 2 in polymer 2 is 3.4x10-6 cm2/s. Determine which  treatment will be selected for treatment of fatty liver disease.

Human Anatomy & Physiology (11th Edition)
11th Edition
ISBN:9780134580999
Author:Elaine N. Marieb, Katja N. Hoehn
Publisher:Elaine N. Marieb, Katja N. Hoehn
Chapter1: The Human Body: An Orientation
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Two proteins are discovered, and both are shown to have a potential in treating fatty liver 
disease. The structural differences of the proteins require them to be delivered using 
spherical nanoparticles made of different polymers. The scientists are trying to decide 
which protein will be more efficient to use in applications where a faster drug release is 
more favorable. Protein 1 is loaded into spherical nanoparticles made of polymer 1 which 
has R=100 nm at a concentration of 50 nM. Protein 2 is loaded into spherical 
nanoparticles made of polymer 2 which has R=250 nm, at a concentration of 50 nM. The 
partition coefficient of polymer 1 is 0.01 and is known to be half of partition coefficient 
of polymer 2. The diffusion coefficient of protein 1 in polymer 1 is 2x10-6 cm2/s, and 
diffusion coefficient of protein 2 in polymer 2 is 3.4x10-6 cm2/s. Determine which 
treatment will be selected for treatment of fatty liver disease.   

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Step 1

There are few points fatty liver syndrome . These are as follows :

  • We know that fatty liver syndrome is the deposition of fat on liver so the result will be liver damage.
  • There are mainly two types of fatty liver syndrome one is alcoholic and other is non alcoholic.
  • There are many risk factor also as it causes obesity ,diabetes 

There are treatment like weight loss as it helps in reduces the fat in liver . 

There are various precaution like there should no alcohol intake , Eat healthy diet and do regular exercise.

As such medicines are not developed for this disease

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