This type of negative feedback loop ensures that ilvC transcription will always be repressed when llvY levels low, and ilvC will be transcribed highly when llvY levels are high. This type of negative feedback regulation ensures that ilvY is never transcribed. Since IlvY is a transcriptional repressor, it will slow down cell growth by blocking transcription. So, IlvY represses it's own transcription so no llvY can ever be made, and the cell can grow. This type of negative feedback loop ensures that there is always a moderate amount of llvY. When lvY levels too low, transcription from the promoter will increase since IIVY won't be able to repress it's own promoter. 1 negative feedback also ensures that lvY levels don't rise too high - when llvY levels are high, then transcripti from the ilvY promoter is tightly repressed by all the llvY protein, so no more is made. This type of negative feedback allows levels of llvY to increase to very high levels when they are needed. Ilv represses transcription from its own promoter, so llvY levels will increase exponentially once a threshold leve IlvY protein is made.
This type of negative feedback loop ensures that ilvC transcription will always be repressed when llvY levels low, and ilvC will be transcribed highly when llvY levels are high. This type of negative feedback regulation ensures that ilvY is never transcribed. Since IlvY is a transcriptional repressor, it will slow down cell growth by blocking transcription. So, IlvY represses it's own transcription so no llvY can ever be made, and the cell can grow. This type of negative feedback loop ensures that there is always a moderate amount of llvY. When lvY levels too low, transcription from the promoter will increase since IIVY won't be able to repress it's own promoter. 1 negative feedback also ensures that lvY levels don't rise too high - when llvY levels are high, then transcripti from the ilvY promoter is tightly repressed by all the llvY protein, so no more is made. This type of negative feedback allows levels of llvY to increase to very high levels when they are needed. Ilv represses transcription from its own promoter, so llvY levels will increase exponentially once a threshold leve IlvY protein is made.
Human Anatomy & Physiology (11th Edition)
11th Edition
ISBN:9780134580999
Author:Elaine N. Marieb, Katja N. Hoehn
Publisher:Elaine N. Marieb, Katja N. Hoehn
Chapter1: The Human Body: An Orientation
Section: Chapter Questions
Problem 1RQ: The correct sequence of levels forming the structural hierarchy is A. (a) organ, organ system,...
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Question
Transcribed Image Text:What is the advantage of using transcriptional reporters to study the activity of a gene's promoter?
No answer text provided.
It allows you to easily measure the approximate, relative transcriptional activity of a single promoter of interest in
the cell in different conditions or genetic strain backgrounds.
It allows you to measure exactly how many MRNA transcripts are being produced from a given promoter every
second.
It allows you to measure the activity of a promoter when only RNA Polymerase is present - transcriptional
reporters are not affected by all the other transcription factors that are present in the cell.
Transcribed Image Text:LysR regulators like llvY repress transcription from their own promoters. This is called a negative
feedback loop. Why might negative feedback be a good way to control expression of a transcriptional
repressor?
This type of negative feedback loop ensures that ilvC transcription will always be repressed when llvY levels are
low, and ilvC will be transcribed highly when llvY levels are high.
This type of negative feedback regulation ensures that ilvY is never transcribed. Since llvY is a transcriptional
repressor, it will slow down cell growth by blocking transcription. So, llvY represses it's own transcription so that
no llvY can ever be made, and the cell can grow.
This type of negative feedback loop ensures that there is always a moderate amount of llvY. When IlvY levels fall
too low, transcription from the promoter will increase since IlvY won't be able to repress it's own promoter. This
negative feedback also ensures that IlVY levels don't rise too high - when llvY levels are high, then transcription
from the ilvY promoter is tightly repressed by all the IlvY protein, so no more is made.
This type of negative feedback allows levels of IlvY to increase to very high levels when they are needed. IlvY
represses transcription from its own promoter, so llvY levels will increase exponentially once a threshold level of
IlvY protein is made.
Expert Solution
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Hi! Since you posted many questions, we will be answering the 1 for you. Please post the other questions separately if you want them answered.
A repressor is a macromolecule that has a suppressive effect on gene expression. As a result, these are proteins that bind to deoxyribonucleic acid and either prevent or slow down the ribonucleic acid transcription machinery from transcribing that deoxyribonucleic acid.
A regulatory gene creates a tiny protein molecule referred to as a represser, which controls the operon. The repressor binds to the factor, preventing it from starting the production of the macromolecule that the deoxyribonucleic acid is concerned with.
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