Using pencil and paper, what is the frequency of feebleminded individuals in the population? (Use the Hardy-Weinberg equilibrium principle). If we had a population of 1000 individuals, how many would be feebleminded? How many would be carriers for feeblemindedness? How many would be homozygous normalminded? • If a eugenic sterilization law were universally enforced, such that all feebleminded individuals were sterilized before reaching sexual maturity, what would be the fitnesses of the three genotypes? Explain. • Using pencil and paper, what would be the frequency of allele A1 after a single generation of eugenic sterilization. Use the numbers you calculated in part a, and assume that every nonsterilized individual makes exactly 10 gametes. What is the total number of gametes? What fraction carry allele A1? After a single round of random mating, what would be the frequency of each genotype? How effective is eugenic sterilization at reducing the frequency of feeblemindedness (compare the frequency of feeblemindedness before and after sterilization)

Human Anatomy & Physiology (11th Edition)
11th Edition
ISBN:9780134580999
Author:Elaine N. Marieb, Katja N. Hoehn
Publisher:Elaine N. Marieb, Katja N. Hoehn
Chapter1: The Human Body: An Orientation
Section: Chapter Questions
Problem 1RQ: The correct sequence of levels forming the structural hierarchy is A. (a) organ, organ system,...
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Imagine, as early 20th century eugenicists did, a single locus at which there is a gene controlling
strength of mind. A2 is the allele for normalmindedness; A1 is the allele for feeblemindedness.
A2 is dominant over A1. Imagine, as Henry H. Goddard (1914) did, that allele A1 = 0.1.
• Using pencil and paper, what is the frequency of feebleminded individuals in the
population? (Use the Hardy-Weinberg equilibrium principle). If we had a population of
1000 individuals, how many would be feebleminded? How many would be carriers for
feeblemindedness? How many would be homozygous normalminded?
• If a eugenic sterilization law were universally enforced, such that all feebleminded
individuals were sterilized before reaching sexual maturity, what would be the fitnesses
of the three genotypes? Explain.
• Using pencil and paper, what would be the frequency of allele A1 after a single
generation of eugenic sterilization. Use the numbers you calculated in part a, and
assume that every nonsterilized individual makes exactly 10 gametes. What is the total
number of gametes? What fraction carry allele A1? After a single round of random
mating, what would be the frequency of each genotype? How effective is eugenic
sterilization at reducing the frequency of feeblemindedness (compare the frequency of
feeblemindedness before and after sterilization)?

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