Use the illustration as a reference to select the correct statements transcription factors of eukaryotic cells Other transcription factor proteins Gene Enhancers Promoter 3 This protein complex makes it easier for RNA polymerase to attach to the promoter and start transcribing a gene 1 Activator proteins bind to pieces of DNA called enhancers. Their binding causes the DNA A to bend, bringing them near a gene promoter, even though they may be thousands of base pairs away RNA polymerase Activator proteins 2 Other transcription factor proteins join the activator proteins, forming a protein complex which binds to the gene promoter. note This dagram simplifies the DNA gready-promoters, enhancers and risulators can bedoens or even hundreds of base pais long www 4 An insulator can stop the enhancers from binding to the promoter, if a protein called CTCF (named for the sequence CCCTC which occurs in all insulators) binds to it. CHALE Methyl groups CTCF (CCCTC-binding factor) -Insulator 5 Methylation, the addition of a methyl group to the C nudeotides, prevents CTCF from attaching to the insulator, turning it off, allowing the enhancers to bind to the promoter. RNA polymerase binds to the promoter to start transcribing a gene The illustration shows the beginning of translation RNA polymerase participates in both RNA transcription and DNA synthesis Enhancers; promoter and gene are all fragments of DNA The illustration shows how transcription starts in both eukaryotes and prokaryotes Activator proteins bind to DNA fragments called enhancers Transcription factor proteins bind to the promoter to facilitate RNA polymerase activity

Human Anatomy & Physiology (11th Edition)
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Chapter1: The Human Body: An Orientation
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Use the illustration as a reference to select the correct statements
transcription factors
of eukaryotic cells
00
Other transcription
factor proteins
Gene
Enhancers
Promoter
3 This protein complex makes it easier
for RNA polymerase to attach to the
promoter and start transcribing
a gene
1 Activator proteins bind to pieces of
DNA called enhancers. Their binding
causes the DNA to bend, bringing
them near a gene promoter, even
though they may be thousands of
base pairs away.
RNA polymerase
Activator proteins
note
This dagram simplifies the DNA
- A
4 An insulator can stop the enhancers
from binding to the promoter, if a
protein called CTCF (named for
the sequence CCCTC, which occurs
in all insulators) binds to it.
2 Other transcription factor proteins
join the activator proteins, forming
a protein complex which binds to
the gene promoter.
Methyl groups
CTCF
(CCCTC-binding factor)
-Insulator
5 Methylation, the addition of
a methyl group to the C
nudeotides, prevents CTCF
ulator,
enhancers to bind to the promoter.
RNA polymerase binds to the promoter to start transcribing a gene
The illustration shows the beginning of translation
RNA polymerase participates in both RNA transcription and DNA synthesis
Enhancers; promoter and gene are all fragments of DNA
The illustration shows how transcription starts in both eukaryotes and prokaryotes
Activator proteins bind to DNA fragments called enhancers
Transcription factor proteins bind to the promoter to facilitate RNA polymerase activity
Transcribed Image Text:Use the illustration as a reference to select the correct statements transcription factors of eukaryotic cells 00 Other transcription factor proteins Gene Enhancers Promoter 3 This protein complex makes it easier for RNA polymerase to attach to the promoter and start transcribing a gene 1 Activator proteins bind to pieces of DNA called enhancers. Their binding causes the DNA to bend, bringing them near a gene promoter, even though they may be thousands of base pairs away. RNA polymerase Activator proteins note This dagram simplifies the DNA - A 4 An insulator can stop the enhancers from binding to the promoter, if a protein called CTCF (named for the sequence CCCTC, which occurs in all insulators) binds to it. 2 Other transcription factor proteins join the activator proteins, forming a protein complex which binds to the gene promoter. Methyl groups CTCF (CCCTC-binding factor) -Insulator 5 Methylation, the addition of a methyl group to the C nudeotides, prevents CTCF ulator, enhancers to bind to the promoter. RNA polymerase binds to the promoter to start transcribing a gene The illustration shows the beginning of translation RNA polymerase participates in both RNA transcription and DNA synthesis Enhancers; promoter and gene are all fragments of DNA The illustration shows how transcription starts in both eukaryotes and prokaryotes Activator proteins bind to DNA fragments called enhancers Transcription factor proteins bind to the promoter to facilitate RNA polymerase activity
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