The thiolate anion of CoA acts as a/an nucleophile attacking the carbonyl carbon of the enzyme bound intermediate, displacing AMP and forming a fatty acyl CoA.

Q: Acetyl-CoA + HCO3- → Malonyl-CoA However, the ΔG of this reaction is much greater than zero. In…

A: The formation of malonyl-CoA from acetyl-CoA is an irreversible three-step process, catalyzed by…

Q: What kind of inhibitor is threo-sphingosine? Explain this type of inhibition.

A: Introduction:  Enzymes are the catalyst of life. Enzyme inhibitor is defined as a substance which…

Q: Which of the following is most helpful in ensuring that wasteful (unproductive) hydrolysis of acetyl…

A: " Since you're posted multiple questions I will provide the solution  of only firstquestion you ask…

Q: Although both acetyl-CoA and succinyl-CoA are high-energy thioesters, their chemical energy is used…

A: A tricarboxylic acid (TCA) cycle, commonly known as the Krebs or citric acid cycle, is the primary…

Q: Mercuric ion and methanol are inhibitors of alcohol dehydrogenase. Explain.

A: Alcohol (ADH) dehydrogenase is an enzyme that helps in the interconversion of alcohol into ketones…

Q: Compare and contrast Pyruvate Dehydrogenase with a-ketoglutarate dehydrogenase Outline the…

A: Enzymes are essential for the functioning of living cells and play a crucial role in maintaining…

Q: Consider a preparation that contains all the enzymes and cofactors necessary for fatty acid…

A: Questions 1 - This process takes place in the cytoplasm of the cell. Most of the acetyl-CoA which is…

Q: Look at the synthesis of citryl CoA by citrate synthase in the figure.  Which of the 4 general…

A: Citrate synthase is an important enzyme in citric acid cycle that catalyses the conversion of oxalo…

Q: In order to provide the acetyl-CoA molecules to produce 3 equivalents of palmitic acid, how many…

A: Glucose is generally a monosaccharide that has six carbon atoms and an aldehyde group and it is…

Q: Citrate synthase is regulated by another metabolite that has the opposite effect (i.e., stimulates…

A: The citric acid cycle carries out the complete oxidation of acetyl CoA molecules that are obtained…

Q: Fatty acid synthesis requires the activation of acetyl CoA to malonyl CoA. However, its condensation…

A: Fatty acids are broken down to acetyl Co-A and the precursor for the fatty acid synthesis is acetyl…

Q: During the process of synthesizing palmitate (C16), an acyl ACP __________. For the sake of this…

A: Fatty acid β-oxidation is the process by which fatty acids are broken down to produce energy.

Q: One    metabolic    scenario that    leads to insulin    resistance is the elevation    of the…

A: Insulin resistance is defined as the inactivity of insulin in its target cells. The examples of…

Q: Beta-Oxidation of a 15:14⁹ fatty acid will result in the production of which of the following? 7…

A: The given fatty acid is composed of 15 carbon and it has a single double bond present in it. It…

Q: A biological Claisen reaction occurs in the conversion of two acetyl CoA molecules to one…

A: Introduction: The condensation reactions involve the formation of new carbon-carbon bonds. The most…