Fatty acids are activated for breakdown through the action of acyl-CoA synthestase. Which of the followingstatements regarding acyl-CoA synthetase is not true?● It catalyzes the addition of CoA to the fatty acidOne of the products of the reaction is ADP.O The free energy change for the reaction catalyzed by this reaction is close to 0 kJ/mol, but the subsequent hydrolysis ofpyrophosphate drives the reaction forward.O The reaction results in the formation of a thioester bond.

Fatty acids are oxidised in the mitochondria. The fatty acid cannot enter the mitochondria but fatty…

Answered: Fatty acids are activated for breakdown…

Biochemistry

9th Edition

ISBN:9781319114671

Author:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.

Publisher:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.

Chapter1: Biochemistry: An Evolving Science

Section: Chapter Questions

Problem 1P

See similar textbooks

Similar questions

Fill in the blanks below (input numbers only!) about the metabolism of hexanoic acid, a fatty acid that is one of the components of vanilla, and whose formula is CH3(CH2)4COOH: First, the fatty acid is activated by attaching CoA, which costs ATP molecules. The fatty acid is then broken down through a beta-oxidation spiral, to make acetyl CoA molecules. This will require "turns" of the beta-oxidation process. Since each turn of the cycle yields ATP molecules, and each acetyl COA will yield ATP molecules by going through the rest of its metabolism, the net ATP molecules produced from one molecule of this fatty acid will be
ATP, like ADP and AMP, is a competitive inhibitor of NADH binding to malate dehydrogenase. Provide a structural explanation for this inhibition.
Match the following metabolites with the correct metabolic pathway A. Kreb's cycle v Propionyl-CoA B. Soluble fiber fermenta v Dihydroxy acetone phosphate C. Cholesterol synthesis v succinyl co-A D. glycolysis v Hydroxy methyl glutaryl coA E. Beta oxidation v Hydroxy-butyrate QUESTION 28 When a 23 Carbon fatty acid is metaboližed, what is the total number of (GROSS) ATP produced 7 QUESTION 29 When a 23 Carbon fattv acid is metabolized the numbher of NET ATD produced is? Click Save and Submit to save and submit. Click Save All Answers to save all answers. Esc F3 Fs
9. The equation below depicts the first step of the citric acid cycle. H0 CoA-SH CH-C + 0=C-CO0 HO C-COO citrate s-COA ČH2-COO synthase ČH2 -CO0 Citrate Acetyl-CoA Oxaloacetate AG" = -32.2 kJ/mol a) Explain the chemical conversions that take place during this step. b) Why is this reaction energetically favorable? Explain.
The following reaction, the last reaction in beta-oxidation, is an example of a: Enzyme Enzyme-H S-CoA S-COA H2C H3C CoA s–CoA C H2 CH2 R S-COA S-COA S-COA O A. Nucleophilic acyl substitution O B. Electrophilic addition OC. Nucleophilic addition D. Aldol condensation O E. Hydrohalogenation
The first step of gluconeogenesis involves the carboxylation of pyruvate and has a large negative delta G (i.e very exergonic). Explain how it is possible that this step can be exergonic if we know that adding CO2 onto molecules is fundamentally a destabilizing phenomenon?
The lipase substrate emulsion contains 0.500 mg of olive oil per 3 mL Also, the molar mass of the olive oil is 885 g/mol. If all of the olive oil in a 3 mL reaction is "digested" by pancreatic lipase in a reaction, how many molecules of olive oil have been degraded?
Provide a reasonable step-wise mechanism for the reaction below, involving TPP as acoenzyme (can abbreviate the pyrophosphate as R), and invoking any general acids or base fromacetolactate synthase that you might need .

Recommended textbooks for you

Biochemistry

ISBN:

9781319114671

Author:

Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.

Publisher:

W. H. Freeman

Lehninger Principles of Biochemistry

Biochemistry

ISBN:

9781464126116

Author:

David L. Nelson, Michael M. Cox

Publisher:

W. H. Freeman

Fundamentals of Biochemistry: Life at the Molecul…

Biochemistry

ISBN:

9781118918401

Author:

Donald Voet, Judith G. Voet, Charlotte W. Pratt

Publisher:

WILEY

Biochemistry

ISBN:

9781319114671

Author:

Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.

Publisher:

W. H. Freeman

Lehninger Principles of Biochemistry

Biochemistry

ISBN:

9781464126116

Author:

David L. Nelson, Michael M. Cox

Publisher:

W. H. Freeman

Fundamentals of Biochemistry: Life at the Molecul…

Biochemistry

ISBN:

9781118918401

Author:

Donald Voet, Judith G. Voet, Charlotte W. Pratt

Publisher:

WILEY

Biochemistry

ISBN:

9781305961135

Author:

Mary K. Campbell, Shawn O. Farrell, Owen M. McDougal

Publisher:

Cengage Learning

Biochemistry

ISBN:

9781305577206

Author:

Reginald H. Garrett, Charles M. Grisham

Publisher:

Cengage Learning

Fundamentals of General, Organic, and Biological …

Biochemistry

ISBN:

9780134015187

Author:

John E. McMurry, David S. Ballantine, Carl A. Hoeger, Virginia E. Peterson

Publisher:

PEARSON

SEE MORE TEXTBOOKS