which substrate molecule serves as the phosphate donor during substrate-level phosphorylation in step 10 of glycosis and the succinyl CoA-succinate step of the Krebs Cycle?
Electron Transport Chain
The electron transport chain, also known as the electron transport system, is a group of proteins that transfer electrons through a membrane within mitochondria to create a gradient of protons that drives adenosine triphosphate (ATP)synthesis. The cell uses ATP as an energy source for metabolic processes and cellular functions. ETC involves series of reactions that convert redox energy from NADH (nicotinamide adenine dinucleotide (NAD) + hydrogen (H)) and FADH2(flavin adenine dinucleotide (FAD)) oxidation into proton-motive force(PMF), which is then used to synthesize ATP through conformational changes in the ATP synthase complex, a process known as oxidative phosphorylation.
Metabolism
Picture a campfire. It keeps the body warm on a cold night and provides light. To ensure that the fire keeps burning, fuel needs to be added(pieces of wood in this case). When a small piece is added, the fire burns bright for a bit and then dies down unless more wood is added. But, if too many pieces are placed at a time, the fire escalates and burns for a longer time, without actually burning away all the pieces that have been added. Many of them, especially the larger chunks or damp pieces, remain unburnt.
Cellular Respiration
Cellular respiration is the cellular process involved in the generation of adenosine triphosphate (ATP) molecules from the organic nutritional source obtained from the diet. It is a universal process observed in all types of life forms. The glucose (chemical formula C6H12O6) molecules are the preferred raw material for cell respiration as it possesses a simple structure and is highly efficient in nature.
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COA
CH, -C-S
COO
CH2
HO-C-CO0
CH:
Acetyl CoA
CH2
COO
COO
HO
HS-COA
COO
CH2
HO-CH
NADH
C.
CO
HC
CH
NAD.
Oxaloacetate
Citrate
HO- CH
Co
C4
COO
Isocitrate
Malate
NAD,
CO:
cOO-
3.
CH
NADH
H,O
C5
COO
C.
a-Ketoglutarate
CH2
Fumarate
NAD.
COO
NADH
CO2
CH2
FADH,
C4
C=0
C.
FAD
Succinyl CoA
Succinate
COO
CO"
3.
CH2
3.
CH2
GTP
GDP
COO
CH2
C=0
CH2
GTP
GDP
S-COA
CO"
ADP
ATP
Figure 8: The Krebs Cycle
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Section:
1
Regulatory step
Regulatory step
4
H-C =0
HC-OH
ATP
ADP
H-C-OH
HO-H
Dihydroxyacetone-
phosphate
H-C-OH
HO-C-H
H-C-OH
H-C
ATP ADP
C=0
HO-C-H
H-C-OH
HO-C-H
H-C-OH
H-c-OHỌ
H-C-0-P:0
OH H
Trose
phosphate
Fructose
Hexakinase
HO
HO,
Phosphoglucose
-OHO
H-C-o-P:0
bisptvosphate
aldose
Phasphotructo-
H-C-OHO
kinase
H-C-0-P:0
Jsomerase
somerase
H OH
Glyceraldehyde-
H-C-o-pEo 3-phosphate
Glucose
Glucose-6-phosphate
Fructose-6-phosphate Fructose-1,6-biphosphate
H-C-OHO
H
NAD + P,
Glyceraldehyde
3-phosphate
dehydrogenase
NADH + H*
2X
ATP
ADP
H20
ATP
ADP
H-C-O-P#0
H-C-0-P:O
H-C-OHO
H-C OH O Phosphoglycetate H.C-0-PEo Phosphoglycerate
H.COHO
H-C-0-p0
Enolase
Pyruwate
kinase
mutase
KYnase
H-5-H
Phosphoenolpyruvate
(PEP)
2-Phosphoglycerate
3-Phosphoglycerate
1,3-Bisphosphoglycerate
Pyruvate
9.
8.
7
10
Regulatory step
Figure 5: Glycolysis
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Step by step
Solved in 2 steps
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