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The lasonolides are novel polyketides that have displayed remarkable biological activity in vitro against a variety of cancer cell lines. OEt No OH NaBHy OEt OEt OEt OH OH SiMe2Bn R₂SiO R₂SiO Not OEt Li Al4 BnMa Si BnMe₂Si Wittig OH OH OH SiMe2Bn MnO2 OEt OTIPS OTIPS OH OH Part A OTBS + Part B HO OH OH HO OH (-)-lasonolide A NaOH SOCI21 NaOH OH OEt OH HO OH OH OH

The lasonolides are novel polyketides that have displayed remarkable biological activity in vitro against a variety of cancer cell lines. OEt No OH NaBHy OEt OEt OEt OH OH SiMe2Bn R₂SiO R₂SiO Not OEt Li Al4 BnMa Si BnMe₂Si Wittig OH OH OH SiMe2Bn MnO2 OEt OTIPS OTIPS OH OH Part A OTBS + Part B HO OH OH HO OH (-)-lasonolide A NaOH SOCI21 NaOH OH OEt OH HO OH OH OH

Human Anatomy & Physiology (11th Edition)
Human Anatomy & Physiology (11th Edition)
11th Edition
ISBN:9780134580999
Author:Elaine N. Marieb, Katja N. Hoehn
Publisher:Elaine N. Marieb, Katja N. Hoehn
Chapter1: The Human Body: An Orientation
Section: Chapter Questions
Problem 1RQ: The correct sequence of levels forming the structural hierarchy is A. (a) organ, organ system,...
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The lasonolides are novel polyketides that have displayed remarkable biological activity in vitro against a variety of cancer cell lines. OEt No OH NaBHy OEt OEt OEt OH OH SiMe2Bn R₂SiO R₂SiO Not OEt Li Al4 BnMa Si BnMe₂Si Wittig OH OH OH SiMe2Bn MnO2 OEt OTIPS OTIPS OH OH Part A OTBS + Part B HO OH OH HO OH (-)-lasonolide A NaOH SOCI21 NaOH OH OEt OH HO OH OH OH
Transcribed Image Text:The lasonolides are novel polyketides that have displayed remarkable biological activity in vitro against a variety of cancer cell lines. OEt No OH NaBHy OEt OEt OEt OH OH SiMe2Bn R₂SiO R₂SiO Not OEt Li Al4 BnMa Si BnMe₂Si Wittig OH OH OH SiMe2Bn MnO2 OEt OTIPS OTIPS OH OH Part A OTBS + Part B HO OH OH HO OH (-)-lasonolide A NaOH SOCI21 NaOH OH OEt OH HO OH OH OH
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