The following figure shows a screen shot from the UCSC Genome Browser, focusing on a region of the human genome encoding a gene called MFAP3L. (Note hg38 refers to version 38 of the human genome RefSeq) a. Describe in approximate terms the genomic location of MFAP3L. b. Is the gene transcribed in the direction from the centromere-to-telomere or from the telomere-to-centromere? c. How many alternative splice forms of MFAP3L mRNA are indicated by the data? d. How many different promoters for MFAP3L are suggested by the data?
The following figure shows a screen shot
from the UCSC Genome Browser, focusing
on a region of the human genome encoding
a gene called MFAP3L. (Note hg38 refers to
version 38 of the human genome RefSeq)
a. Describe in approximate terms the genomic
location of MFAP3L.
b. Is the gene transcribed in the direction from
the centromere-to-telomere or from the
telomere-to-centromere?
c. How many alternative splice forms of
MFAP3L mRNA are indicated by the data?
d. How many different promoters for MFAP3L
are suggested by the data?
(please do not copy and paste the answer from below. i don't think it is correct.
a. MFAP3L is mostly found in the nucleus in the genome. It is found on chromosome 4 reverse strand. The protein produced by the gene is found in the cell membrane, and it is positioned on the membrane with the carboxyl side of the protein facing the cytosol.
b. The MFAP3L gene is transcribed from the telomere to the centromere.
c. According to the data, there are 11 different splice forms or transcripts of MFAP3L mRNA.
d The data suggests that the MFAP3L gene has two different promoters.)
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