The first page of this chapter displays photos ofRainbow and her clone, CC. Both cats are tabby (theircolored fur has a mottled pattern) and both have whiteregions, mainly on their bellies and legs. However, amajor difference exists in their appearances. Rainbowis a calico tabby; she has black and orange spots controlled by alleles of the X-linked O gene, where thedominant trait is black (O-) and the recessive trait isorange (oo). However, Rainbow’s clone, CC, is ablack tabby; she lacks the orange spots. CC was made by transferring into an enucleatedoocyte a single nucleus from one of Rainbow’s diploid somatic cells. That diploid oocyte, a mimic of afertilized egg, was then implanted in the uterus of asurrogate mother. (The process of cloning by somaticcell nuclear transfer will be described in more detailin Chapter 18.)a. What is Rainbow’s (and CC’s) genotype for theO gene?b. Given that CC was made from a single one ofRainbow’s somatic cell nuclei, explain the difference between CC’s and Rainbow’s appearances.c. Would every clone of Rainbow’s be a black tabbylike CC, or do other possibilities exist? Explain.
The first page of this chapter displays photos of
Rainbow and her clone, CC. Both cats are tabby (their
colored fur has a mottled pattern) and both have white
regions, mainly on their bellies and legs. However, a
major difference exists in their appearances. Rainbow
is a calico tabby; she has black and orange spots controlled by alleles of the X-linked O gene, where the
dominant trait is black (O-) and the recessive trait is
orange (oo). However, Rainbow’s clone, CC, is a
black tabby; she lacks the orange spots.
CC was made by transferring into an enucleated
oocyte a single nucleus from one of Rainbow’s diploid somatic cells. That diploid oocyte, a mimic of a
fertilized egg, was then implanted in the uterus of a
surrogate mother. (The process of cloning by somatic
cell nuclear transfer will be described in more detail
in Chapter 18.)
a. What is Rainbow’s (and CC’s) genotype for the
O gene?
b. Given that CC was made from a single one of
Rainbow’s somatic cell nuclei, explain the difference between CC’s and Rainbow’s appearances.
c. Would every clone of Rainbow’s be a black tabby
like CC, or do other possibilities exist? Explain.
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