Nail-patella syndrome gene is 10 map units from the I gene that determines the ABO blood type on chromosome 9. John’s afflicted mother is type A, while his normal father has type O blood. The Laura’s afflicted mother has type O blood, while her normal father has type B blood. What is their chance of having a normal, type O child.

Nail-patella syndrome gene is 10 map units from the I gene that determines the ABO blood type on chromosome 9. John’s afflicted mother is type A, while his normal father has type O blood. The Laura’s afflicted mother has type O blood, while her normal father has type B blood. What is their chance of having a normal, type O child.

Name: Nail-patella syndrome gene is 10 map units from the I gene that determ
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Description: Nail-patella syndrome gene is 10 map units from the I gene that determines the ABO blood type on chromosome 9. John’s afflicted mother is type A, while his normal father has type O blood. The Laura’s afflicted mother has type O blood, while her norma

Human Heredity: Principles and Issues (MindTap Course List)

11th Edition

ISBN:9781305251052

Author:Michael Cummings

Publisher:Michael Cummings

Chapter6: Cytogenetics: Karyotypes And Chromosome Aberrations

Section: Chapter Questions

Problem 2QP: Given the karyotype shown at right, is this a male or a female? Normal or abnormal? What would the...

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Hemophilia is an X-linked disease associated with the inability to produce specific proteins in the blood-clotting pathway. Shown above is a family pedigree tree in which family members afflicted with the disease are shown with filled-in squares (male) or circles (females). A couple is trying to determine the likelihood of passing on the disease to their future children (represented by the ? symbol above) because the hemophilia runs in the woman’s family 4.Assuming that the woman in the couple is a carrier, what is the probability that the couple’s first son will have hemophilia?
The mother of a family with 10 children has blood typeRh+. She also has a very rare condition (elliptocytosis,phenotype E) that causes red blood cells to be oval rather than round in shape but that produces no adverseclinical effects. The father is Rh− (lacks the Rh+ antigen)and has normal red blood cells (phenotype e). The children are 1 Rh+ e, 4 Rh+ E, and 5 Rh− e. Information isavailable on the mother’s parents, who are Rh+ E andRh− e. One of the 10 children (who is Rh+ E) marriessomeone who is Rh+ e, and they have an Rh+ E child.a. Draw the pedigree of this whole family.b. Is the pedigree in agreement with the hypothesisthat the Rh+ allele is dominant and Rh− is recessive?c. What is the mechanism of transmission ofelliptocytosis?d. Could the genes governing the E and Rh phenotypesbe on the same chromosome? If so, estimate the mapdistance between them, and comment on your result
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Shown above is a family pedigree tree in which family members afflictedwith the disease Haemophilia are shown with filled-in squares (male) or circles (females). A couple is trying to determine the likelihood of passingon the disease to their future children (represented by the ? symbolabove) because the hemophilia runs in the woman’s family. Turner syndrome is a disease in which an individual is bornwith only a single X chromosome. Suppose the woman in thecouple is a carrier for hemophilia and has a child with Turnersyndrome. Would this child have the disease?
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My Question is what is the probability their first child will have hemophilia and drawn pedigrees for family members with genotypes. My explantion so far: A man has both X and Y chromosomes as sex chromosomes in his body. Here, though the brother of the man is hemophiliac, a man can’t be a carrier of hemophilia. So, it can be said that his chromosome is “XnY”.Here, the “n” stands for “normal”.Though the paternal uncle is hemophiliac, a man cannot be a carrier of hemophilia, his niece will not be a career. So it can be said that the woman is also not a carrier and has the “XnX” chromosome.So, as the mother is not a carrier, their first child does not have a chance of having hemophilia. This can be determined as it is known that there is no hidden carrier of hemophilia in the family.
The X chromosome has a lot of traits for things besides the traits we consider female. It carries traits forthings like the ability of your blood to clot correctly and the ability to see differences in the colors red andgreen. If you blood doesn’t clot correctly, it’s called Hemophilia. If you can’t see the difference betweenred and green, you are colorblind. Therefore, these are referred to as X-Linked or Sex-Linked Traits.Notice that those are on the X chromosome only. That means they are missing from the Y. In fact, the Y iscalled Y because it is physically missing a section at the end. This means the Y chromosome is missing genes that the X chromosome has. If you are XY, you only haveone copy of the gene, or one allele. Given what we just said above, can a XY parent pass a X-Linked Trait to his XY offspring?
Greg and Susan have Nail- Patella syndrome (NPS). NPS is an autosomal dominant. Greg has a blood in cis infection with NPS inherited from his mother. Greg’s father is normal for NPS and he has O blood. Susan has B blood inherited from her father who is normal for NPS, but Susan has inherited NPS from her mother who has O blood. ABO blood type and NPS are on the same chromosome 9, and they are 8 map units apart. What is the chance that they will have a child that is normal for NPS with B blood? Please leave answers as an uncalculated equation. Please show what chromosome with the specific alleles that is inherited from which individual. What is the chance that they will have a child that is normal for NPS with AB blood? Please show what chromosome with the specific alleles that is inherited from which individual. What is the chance that the child will be normal for NPS, have O blood and be male?
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Hemophilia is another example of a X-linked disease caused when a recessive allele (Xh) is expressed. If a normal male reproduces with a heterozygous normal female, what are the expected genotypes and phenotypes? Will any of their daughters develop hemophilia? As in the previous question, you must also give the gender of the child in your genotype and phenotype descriptions here.