Retinoblastoma can be seen as a familial cancer, inherited in an autosomal recessive manner (RB-/RB-), individuals heterozygous for the RB+ and RB- alleles can develop tumor as a result of…A mitotic crossover that leads to homozygosity for RB+ in some cells and RB- in other cellsA meiotic mutation in the RB+ allele that leads to homozygosity for RB+A somatic mutation in the RB- allele that leads to homozygosity for RB+The fact that RB- is dominant to RB+

Name: Retinoblastoma can be seen as a familial cancer, inherited in an autos
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Description: Retinoblastoma can be seen as a familial cancer, inherited in an autosomal recessive manner (RB-/RB-), individuals heterozygous for the RB+ and RB- alleles can develop tumor as a result of…A mitotic crossover that leads to homozygosity for RB+ in som

The Rb gene is an archetypal tumor suppressor gene. Mutations in this gene result into…

Answered: Retinoblastoma can be seen as a…

Human Heredity: Principles and Issues (MindTap Course List)

11th Edition

ISBN:9781305251052

Author:Michael Cummings

Publisher:Michael Cummings

Chapter12: Genes And Cancer

Section: Chapter Questions

Problem 12QP

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Retinoblastoma can be seen as a familial cancer, inherited in an autosomal recessive manner (RB-/RB-), individuals heterozygous for the RB+ and RB- alleles can develop tumor as a result of…

A mitotic crossover that leads to homozygosity for RB+ in some cells and RB- in other cells
A meiotic mutation in the RB+ allele that leads to homozygosity for RB+
A somatic mutation in the RB- allele that leads to homozygosity for RB+
The fact that RB- is dominant to RB+

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