The figure below shows antibodies bound to repetitive epitopes on the surface of a bacterial pathogen. Even though all of these epitopes are identical, not all of them have antibodies bound to them. The most likely explanation for this failure of antibodies to bind to every possible epitope on the surface of the pathogen is:
The figure below shows antibodies bound to repetitive epitopes on the surface of a bacterial pathogen. Even though all of these epitopes are identical, not all of them have antibodies bound to them. The most likely explanation for this failure of antibodies to bind to every possible epitope on the surface of the pathogen is:
Human Anatomy & Physiology (11th Edition)
11th Edition
ISBN:9780134580999
Author:Elaine N. Marieb, Katja N. Hoehn
Publisher:Elaine N. Marieb, Katja N. Hoehn
Chapter1: The Human Body: An Orientation
Section: Chapter Questions
Problem 1RQ: The correct sequence of levels forming the structural hierarchy is A. (a) organ, organ system,...
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The figure below shows antibodies bound to repetitive epitopes on the surface of a bacterial pathogen. Even though all of these epitopes are identical, not all of them have antibodies bound to them. The most likely explanation for this failure of antibodies to bind to every possible epitope on the surface of the pathogen is:
- There is an insufficient amount of antibody to saturate all the epitopes.
- The pathogen has an immune evasion strategy to avoid antibody binding to all epitopes.
- Some of the epitopes cannot bind antibody due to steric hindrance.
- The antibodies are only able to bind when both antigen-binding sites are engaged on the pathogen surface.
- The epitopes on the pathogen are not all in the same conformation, so not all will bind the same antibody.
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