strep throat is the presence of swollen lymph nodes in the neck. This symptom usually peaks about 2–4 days after the onset of the infection, and is due to: Damage to the pharyngeal epithelium by the bacteria Release of

Human Anatomy & Physiology (11th Edition)
11th Edition
ISBN:9780134580999
Author:Elaine N. Marieb, Katja N. Hoehn
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Chapter1: The Human Body: An Orientation
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Strep throat is commonly caused by group A Streptococcus bacteria. A common symptom of strep throat is the presence of swollen lymph nodes in the neck. This symptom usually peaks about 2–4 days after the onset of the infection, and is due to:

  1. Damage to the pharyngeal epithelium by the bacteria
  2. Release of bacterial PAMPs leading to inflammatory cytokine production
  3. Trapping and activation of antigen-specific lymphocytes in the lymph nodes of the neck
  4. Recruitment of neutrophils to the lymph nodes of the neck
  5. Recruitment of circulating macrophages to the lymph nodes of the neck
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