**Question:**If you think about polymerization like a chemical reaction at equilibrium, how would the concentration of tubulin heterodimers influence the likelihood of microtubule growth versus shrinkage?**Select all that apply.**- [ ] Once a monomer is added to a microtubule, its loss from the microtubule is favorable when the monomer concentration is below the critical concentration.- [ ] Once a monomer is added to a microtubule, its loss from the microtubule is highly unfavorable under most circumstances.- [ ] Once a monomer is added to a microtubule, its loss from the microtubule depends on the monomer concentration.- [ ] Once a monomer is added to a microtubule, its loss is highly favorable under most circumstances.**Buttons:**- Submit- Request Answer

In cell biology, the study of microtubules has high significance. The polymerization and depolymerization of microtubules or spindle fibers have a crucial role in cell architecture.Often microtubules have both plus and minus ends. The polymerization activity is higher at the plus end, whereas the depolymerization activity is higher at the minus end. This polymerization or depolymerization occurs by the addition or deletion of microtubules monomers (tubulin). This depends on the free microtubule monomers. During cell division, for the movement of chromosomes, the microtubules play a big role. Often rapid polymerization and depolymerization occur in them for extension and withdrawal for any cellular movement. Here if it is considered in terms of equilibrium in the chemical reaction, these reactions are highly favorable depending on the concentration of tubulin monomers. So here apart from 'option B', all other options can be correct. Hence, microtubules play a vital role in the cellular movement.