SARS-CoV-2 Spike protein variant Wuhan Alpha Beta Delta Omicron KD, nM 60 9.6 2.4 1.2 2.4 Using the data from the table above, calculate the specificity factor (a) of the interaction between the ACE2 protein and SARS-CoV-2 variant spike proteins at [ACE2] = 1 nM. Assume that the concentration of each of the SARS-CoV-2 variant spike proteins is the same in the binding reaction. Show your work. Now calculate the specificity factor (a) of the same interaction at [ACE2] = 10 nM. Show your work.

Biochemistry
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ISBN:9781319114671
Author:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.
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Chapter1: Biochemistry: An Evolving Science
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Calculate the specificity factor (a) of the interaction between the ACE2 protein and SARS-CoV-2 variant spike proteins at [ACE2] = 1 nM and 10nM. Show work pls

SARS-CoV-2
Spike protein variant
Wuhan
Alpha
Beta
Delta
Omicron
KD, nM
60
9.6
2.4
1.2
2.4
Using the data from the table above, calculate the specificity factor (a) of the
interaction between the ACE2 protein and SARS-CoV-2 variant spike proteins at
[ACE2] = 1 nM. Assume that the concentration of each of the SARS-CoV-2 variant
spike proteins is the same in the binding reaction. Show your work.
Now calculate the specificity factor (a) of the same interaction at [ACE2] = 10 nM.
Show your work.
Transcribed Image Text:SARS-CoV-2 Spike protein variant Wuhan Alpha Beta Delta Omicron KD, nM 60 9.6 2.4 1.2 2.4 Using the data from the table above, calculate the specificity factor (a) of the interaction between the ACE2 protein and SARS-CoV-2 variant spike proteins at [ACE2] = 1 nM. Assume that the concentration of each of the SARS-CoV-2 variant spike proteins is the same in the binding reaction. Show your work. Now calculate the specificity factor (a) of the same interaction at [ACE2] = 10 nM. Show your work.
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