16b) Suppose you have a cell in which the Iron Response Factor (IRF) protein is mutated so that it binds to its binding site, the Iron Response Element (IRE), at all times, whether the intracellular iron concentration is low or high. Describe the effect, if any, that this mutation would have on production of the iron transport protein transferrin. Briefly explain what would happen/why the mutant IRF protein would have the effect you predict.
16b) Suppose you have a cell in which the Iron Response Factor (IRF) protein is mutated so that it binds to its binding site, the Iron Response Element (IRE), at all times, whether the intracellular iron concentration is low or high. Describe the effect, if any, that this mutation would have on production of the iron transport protein transferrin. Briefly explain what would happen/why the mutant IRF protein would have the effect you predict.
Human Anatomy & Physiology (11th Edition)
11th Edition
ISBN:9780134580999
Author:Elaine N. Marieb, Katja N. Hoehn
Publisher:Elaine N. Marieb, Katja N. Hoehn
Chapter1: The Human Body: An Orientation
Section: Chapter Questions
Problem 1RQ: The correct sequence of levels forming the structural hierarchy is A. (a) organ, organ system,...
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Transcribed Image Text:16b) Suppose you have a cell in which the Iron Response Factor (IRF) protein is mutated so that it
binds to its binding site, the Iron Response Element (IRE), at all times, whether the intracellular iron
concentration is low or high. Describe the effect, if any, that this mutation would have on production
of the iron transport protein transferrin. Briefly explain what would happen/why the mutant IRF
protein would have the effect you predict.
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Step 1
Iron is a trace element in our body, which is very important to produce hemoglobin which carries oxygen to our lungs to carry out cellular metabolism to produce energy. Iron also takes part in synthesizing enzymes for oxygen utilization in cell. Iron deficiency is the major cause of anemia in women of reproductive age and in pregnant women.
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