reversible competitive antagonist

Phlebotomy Essentials
6th Edition
ISBN:9781451194524
Author:Ruth McCall, Cathee M. Tankersley MT(ASCP)
Publisher:Ruth McCall, Cathee M. Tankersley MT(ASCP)
Chapter1: Phlebotomy: Past And Present And The Healthcare Setting
Section: Chapter Questions
Problem 1SRQ
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Question 1a. What is the direction of shift of a dose-response curve when a reversible competitive antagonist is present at a fixed concentration?

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  • Left
  • Right
  • Down and right

 

Question 1b. When the antagonist is competitive and reversible how does the Emax change?

  • It is unchanged
  • It is increased
  • It is decreased

 

Question 1c. When the antagonist is competitive and reversible how does the ED50 change?

  • It is unchanged
  • It is increased
  • It is decreased

Question 2a. What is the direction of shift of a dose -response curve when an irreversible competitive antagonist is present at a fixed concentration. 

  • Up
  • Down
  • Left
  • Right
  • Down and right

 

Question 2b. When the antagonist is competitive and irreversible how does the Emax change?

  • It is unchanged
  • It is increased
  • It is decreased

 

Question 2c. When the antagonist is competitive and irreversible how does the ED50 change?

  • It is unchanged
  • It is increased
  • It is decreased

Question 3a. What is the direction of shift of a dose -response curve when a non-competitive antagonist is present at a fixed concentration. 

  • Up
  • Down
  • Left
  • Right
  • Down and right

 

Question 3b. When the antagonist is non-competitive how does the Emax change?

  • It is unchanged
  • It is increased
  • It is decreased

 

Question 3c. When the antagonist is non-competitive how does the ED50 change?

  • It is unchanged
  • It is increased
  • It is decreased
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