Give two COX inhibitors. Why does COX inhibitors act as blood thinner, and antipyretic drugs?

Biochemistry
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ISBN:9781319114671
Author:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.
Publisher:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.
Chapter1: Biochemistry: An Evolving Science
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Give two COX inhibitors. Why does COX inhibitors act as blood thinner, and antipyretic drugs?

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Cyclooxygenase is an enzyme present in the blood vessels and muscle tissues, primarily involved in the sensation of pain. The enzyme is involved in the catalysis of the rate-limiting step in the conversion of arachidonic acid to prostaglandins. 

The prostaglandins are responsible for pain in the sites of injury, inflammation, or infection. Cyclooxygenase (COX) inhibitors reduce pain by inhibiting the biosynthesis of prostaglandins from arachidonic acid. 

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